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Frontiers of Engineering Reports on Leading-Edge Engineering from the 2007 Symposium (2008) / Chapter Skim
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Introduction--Donald J. Leo
Pages 31-32

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From page 31...
... Recent advances in the imaging of biological systems at the appropriate spatial and temporal scales have provided an improved understanding of biological functions such as cell signaling and the dynamic processes associated with protein-protein interactions. Advances in imaging techniques -- when combined with the ability to directly manipulate proteins using mechanical, optical, and magnetic forces -- provide a basis for real-time control of protein conformations for the purpose of directly controlling protein function.
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Key Terms

  • processes associated
  • controlling protein
  • proteins using
  • chemical control
  • protein conformations

  • vaccine development
  • manipulate proteins
  • control protein
  • mechanical manipulation
  • biological functions

  • drug discovery
  • using mechanical
  • directly manipulate
  • central theme
  • magnetic tweezers

  • controlling biological
  • dynamic processes
  • engineering biological
  • tunable biosensors
  • appropriate spatial

  • protein structure
  • temporal scales
  • protein function
  • cell signaling
  • recent advances

  • improved understanding
  • protein conformation
  • directly control
  • explore recent
  • external stimulus


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