The National Children's Study Research Plan A Review (2008) / Chapter Skim
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1 Introduction
1 Introduction
Pages 15-22
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From page 15... ...
BACKGROUND Origins of the NCS The impetus for the NCS, which has been in development since 2000, has many sources. A confluence of concerns led to the establishment, in April 1997 by Executive Order 13045, of the President's Task Force on Environmental Risks and Safety Risks to Children.
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From page 16... ...
At the same time, there was considerable uncertainty about the relationship of other environmental factors to what often appeared to be growing health problems among children, including asthma, autism, developmental disorders, obesity, and childhood cancers. A task force recommendation called for legislation to mandate a large study to identify the risks to children from environmental exposures.
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From page 17... ...
Teams from the Vanguard Centers will be the first to work in their communities to recruit participants, collect and process data, and pilot new research methods for incorporation into the full study. Also in 2005, work began on the NCS research plan, under the general direction of the Interagency Coordinating Committee and with input from the NCS Advisory Committee, the NCS Program Office, and the Coordinating Center.
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From page 18... ...
The plan is to develop protocols and study manuals every 3 years for submission to OMB to cover data collection for participating children ages 3-5, 6-8, and so on through age 21. The Panel's REVIEW After a long development period and uncertain funding, the NCS is scheduled to begin implementation with enrollment of participants in the seven Vanguard Centers in 2008, followed by enrollment in additional centers beginning in 2009.
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From page 19... ...
Topics to be addressed include proposed outcomes and hypotheses; proposed measures of environmental exposure, genetic makeup, family and community environment, and personal characteristics; proposed data collection and analysis methods; and other aspects of the study's research plan. To address this request, the NRC appointed the Panel to Review the National Children's Study Research Plan, a group of 12 people representing a range of expertise related to the scope of the study.
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From page 20... ...
It covers the wide range of exposures planned for measurement in the NCS (which include the physical environment, chemical exposures, psychosocial and biological exposures, and genetic makeup) , the equally wide range of outcomes planned for measurement in the NCS (which include pregnancy outcomes, neurodevelopment and behavior, child health and development, asthma, obesity, injury, and reproductive outcomes)
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From page 21... ...
• Does the research plan set forth an appropriate conceptual frame work for guiding the design of the study? • Does it identify sufficient and appropriate organizing hypotheses for guiding data collection and analysis for the study?
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From page 22... ...
• Does the research plan provide information on the NCS data col lection strategies to maximize initial and follow-up study response rates to ensure quality data collection? • Does the research plan address appropriate analytic and data dis semination approaches to ensure that the study research goals are achieved?
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