Diet and Health Implications for Reducing Chronic Disease Risk (1989) / Chapter Skim
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25 Hepatobiliary Disease
25 Hepatobiliary Disease
Pages 633-636
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From page 633... ...
Cirrhosis may be caused by viral hepatitis, hemochromatosis, obstructive lesions of the biliary system, congestive heart failure, and chronic alcoholism. Specific causes of liver cirrhosis cannot be determined from conventional vital statistics, particu~arty from mortality statistics based on death 633 certificates, even in technically developed countries.
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From page 634... ...
However, more recent experiments have demonstrated that alcohol produces liver toxicity independently of the adverse effects of nutrient deficiencies, and cirrhosis has been reproduced in baboons by alcohol in the absence of nutrient deficiencies (Lieber et al., 1975; Popper and Lieber, 1980; see also Chapter 16~. Evidence Associating Nondietary Factors with Cirrhosis of the Liver Genetic Factors It has long been known that alcoholism clusters in families, and rapidly accumulating evidence indicates that certain genotypes are more susceptible (see Chapters 4 and 16~.
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From page 635... ...
SUMMARY Alcoholic cirrhosis and cholesterol gallstones are the major diseases of the liver and biliary system in the United States. Alcoholic cirrhosis results from prolonged and excessive consumption of alcoholic beverages.
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