Medical Isotope Production Without Highly Enriched Uranium (2009) / Chapter Skim
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Appendix D: Alternative Molybdenum-99 Production Processes
Appendix D: Alternative Molybdenum-99 Production Processes
Pages 184-189
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From page 184... ...
The rate of production, which is of interest here, is proportional to several conditions as illustrated in the equation below: R∝nφσ where R = rate of reaction (i.e., number of reactions per unit time and volume) , which is related to the amount of the new substance that can be produced n = the number of target nuclei present (i.e., the target nuclei density in atoms per unit volume)
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From page 185... ...
, which is illustrated schematically in Figure D.2. The fission cross section for thermal fission of U-235 is approximately 600 barns which represents a very high probability.
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From page 186... ...
Specific activity is defined as the amount of radioactivity per unit mass as is usually e xpressed in terms of Becquerel's per gram or curies per gram. Delft University researchers are examining the feasibility of using Szilard Chalmers reactions to increase specific activities.
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From page 187... ...
99Mo 98Mo(n,γ) 99Mo 99Mo Produces high specific activity Produces low specific activity Mo-99 Requires enriched 235U target Requires highly enriched Mo-98 target Complex chemical processing Simple chemical processing Requires dedicated processing facility Requires high flux neutron source Generates high-level radioactive waste Generates minimal waste SOURCE: Modified from S
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From page 188... ...
The production rate of Mo-99 from most reasonable target materials would be at best many orders of magnitude lower than the reactor methods and two orders of magnitude lower than the above accelerator reactions and thus not a viable approach. From this analysis there are few viable alternative approaches to the supply of Mo-99 or Tc-99m for widespread distribution.
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From page 189... ...
Oak Ridge National Laboratory Report No.
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