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Microbial Evolution and Co-Adaptation A Tribute to the Life and Scientific Legacies of Joshua Lederberg: Workshop Summary (2009) / Chapter Skim
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Appendix C: Glossary
Pages 280-286

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From page 280...
... . Affymetrix chip: A type of DNA microarray gene chip that contains up to 500,000 unique probes corresponding to tens of thousands of gene expression measurements (http://cnx.org/content/m12387/latest/)
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From page 281...
... Spacers are usually unique in a genome. Some spacer sequences match sequences in phage genomes; it is proposed that these spacers derive from phage and subsequently help protect the cell from infection (http://crispr.u-psud.fr/ crispr/CRISPRHomePage.php?
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From page 282...
... Hydrothermal vent ecosystems: The community of organisms that thrives in the extreme heat and mineral-rich waters surrounding hydrothermal vents (geysers on the sea floor)
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From page 283...
... The lymph nodes produce white blood cells and filter bacteria and cancer cells that may travel through the system (http://www.everythingbio. com/glos/definition.php?
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From page 284...
... . Neutrophil: Most common blood leukocyte; a short-lived phagocytic cell of the myeloid series, which is responsible for the primary cellular response to an acute inflammatory episode, and for general tissue homeostasis by removal of damaged material (http://www.mblab.gla.ac.uk/~julian/Dict.html)
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From page 285...
... Many phages have proved useful in the study of molecular biology and as vectors for the transfer of genetic information between cells. Lytic phage (e.g., the T series phage that infect Escherichia coli [coliphages]
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From page 286...
... Virulence factors include bacterial toxins, cell surface proteins that mediate bacterial attachment, cell surface carbohydrates and proteins that protect a bacterium, and hydrolytic enzymes that may contribute to the pathogenicity of the bacterium (http://www.mgc.ac.cn/VFs/main.htm)
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Key Terms

  • virulence factors
  • adaptive immune
  • phagocytic cell
  • lymph nodes
  • cell surface

  • staph bacteria
  • surface carbohydrates
  • lives inside
  • include methicillin
  • lambda bacteriophage

  • phylogenetic profiling
  • causative agent
  • vent crabs
  • cell derived
  • produce white

  • microbial phylotype
  • energy source
  • active substance
  • single microbial
  • preexisting defenses

  • identical sequences
  • acute inflammatory
  • pathogenic bacteria
  • short palindromic
  • viral infection

  • greatly exceeds
  • sea floor
  • initiates events
  • damaged material
  • antibiotics include


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