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Assessing and Improving Value in Cancer Care Workshop Summary (2009) / Chapter Skim
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Glossary
Pages 119-124

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From page 119...
... Bevacizumab is also used in the treatment of advanced, recurrent, or metastatic non-squamous non small cell lung cancer, in combination with carboplatin and paclitaxel, or other cancer drugs, and metastatic HER2-negative breast cancer, in combination with paclitaxel. Biomarker -- a biochemical substance found in blood, other body fluids, or tissues used as an indicator of a biologic state that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or a response to therapeutic intervention.
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From page 120...
... Clinical endpoint -- a characteristic or variable that reflects how a patient feels, functions, or survives in response to a medical intervention. Clinical practice guidelines -- systematically defined statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances.
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From page 121...
... -- a drug used to treat locally advanced or metastatic non-small cell lung cancer and other cancers. It targets epidermal growth factor receptor tyrosine kinase, and specific genetic mutations correlate to patients' response to the drug.
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From page 122...
... Large, simple trial -- prospective, randomized controlled trials that use large numbers of patients, broad patient inclusion criteria, multiple study sites, minimal data requirements, and electronic registries; their purposes include detecting small and moderate treatment effects, gain ing effectiveness data, and improving external validity. Medicare -- a public health care program for individuals aged 65 and older, those who have permanent kidney failure, and people with certain disabilities.
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From page 123...
... -- a unit of health care outcomes that adjusts gains (or losses) in years of life subsequent to a health care
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From page 124...
... -- a comparable service measure used to permit comparison of the amounts of resources required to perform various health care services. It is determined by assigning weight to such fac tors as personnel time, level of skill, and sophistication of equipment required to render patient services.
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Key Terms

  • growth factor
  • antibody drug
  • randomized controlled
  • factor receptor
  • monoclonal antibody

  • regulatory submission
  • controlled trial
  • care services
  • trials conducted
  • epidermal growth

  • care costs
  • breast cancer
  • costs covered
  • cell lung
  • lung cancer

  • insured individual
  • care plan
  • patient services
  • cancer biomarker
  • analytical frameworks

  • study sites
  • locally advanced
  • receptor tyrosine
  • electric shock
  • purposes include

  • iiia trials
  • systematic evaluation
  • clinical trials
  • including physical
  • carefully managed


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