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Pages 289-298

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From page 289...
... 231, 234 combat exposure and, 121 derivative studies, 42, 43, 45, 54 conclusions, 4, 8, 129, 257 environmental exposures and, 190 diagnosis, 126, 127 miscarriages and stillbirths, 193, 201 female veterans, 231 primary studies, 189-190, 191, 200-201 hospitalization study, 128 reference study, 51, 53-54 incidence, 127, 128, 134 registries, 189-190, 192 latency, 8, 9, 258 secondary studies, 190-191, 192 mortality studies, 75, 125, 128 updated and supplemental literature, 191-192 neurotoxin exposure and, 128-129 Volume 4 summary, 4, 19, 189-191 pathogenesis, 126, 128 Bladder infections, 181, 182 primary studies, 127, 129, 133-134 Blood and blood-forming organs, diseases of, 7 research recommendations, 9, 10, 260-261 conclusions, 8, 85, 257 risk factors, 126, 127, 275 hospitalizations, 83-88 secondary studies, 128, 129 latency, 85 updated and supplemental literature, 128-129 mortality studies, 85 Volume 4 summary, 4, 15, 19, 127-128 nerve-agent exposure and, 84, 87 Anemia, 83 oil-well fire smoke exposure and, 84, 87 Animal studies, 3, 15, 25, 129, 275-276 primary studies, 83-84, 86-88 Anthrax vaccine, 14, 57 secondary studies, 84 Anxiety disorders, 17, 19, 42, 50, 63, 99, 100, 101, 102, updated and supplemental literature, 83-84 103-104, 105, 106, 107, 110, 111, 113, 114, 154, 160, Body mass index (BMI)
From page 290...
... , 7. See also Cancer Multisymptom illnesses all cancers, 8, 74-75, 80-82, 257 chemical sensitivity and, 45 brain cancer, 2, 9, 10, 20, 73-74, 75, 76, 78, 79, 125, comorbidities, 157, 163 231, 261 conclusions, 8, 214, 256 conclusions, 8, 78, 257 definition, 210-211, 212 deployment status and, 74-80 diagnosis, 41, 211 derivative studies, 42, 44, 52 in disabled veterans, 52, 214, 220 digestive tract, 76 etiology, 121, 211 hospitalization studies, 73, 74, 75-76, 80, 81 identification of predictors, 42 incidence, 42, 52, 57, 78 mental and behavioral disorders and, 102 latency, 8, 28, 41, 73, 74, 78 multisymptom illnesses, 60, 207, 211 leukemias and lymphomas, 73 oil-fire smoke exposure and, 214 mortality studies, 73, 74-75, 76, 78, 79, 80, 81, 82, pesticide exposure and, 52, 55, 213, 214 125, 226-227 prevalence, 46, 47, 53, 55, 60, 61, 213, 214 nerve agent exposure and, 73-74, 75, 77, 78, 79 primary studies, 211-212, 219-220 oil-well fire smoke and, 74, 75, 78 pyridostigmine bromide and, 55, 213, 214 pesticide exposure and, 78 secondary studies, 212-213 prevalence, 76, 77 threat of chemical weapons and, 55, 212, 213 primary studies, 75-76, 79-82, 125 updated and supplemental literature, 213-214, 220 recommendation, 78 Volume 4 summary, 19, 211-213 registry data, 9 war stress and, 102, 213 research recommendations, 9, 10 Chronic multisymptom illness (CMI)
From page 291...
... , 4, conclusions, 8, 159-161, 256 32, 175-176 diagnosis, 154-155, 160 Contact dermatitis, 164 hospitalization studies, 155-156, 158, 162 Coronary heart disease, 135 mortality, 158, 159 Crohn's disease, 155 neurobehavioral performance, 118, 120 Cyclosarin. See Nerve-agent exposure pesticide/insecticide exposure and, 56 Cytomegalovirus, 213 prevalence, 57 primary studies, 155-156, 162-163 D pyridostigmine bromide exposure and, 159 research needs, 261 Danish Peacekeeper Studies, 43, 56 secondary studies, 156 derivative studies, 43, 56 smoke from buring waste or manure and, 56 diseases of the digestive system, 156-157 updated and supplemental epidemiologic literature, multisymptom illnesses, 206, 217 156-159 reference study, 43, 56 Volume 4 summary, 3, 19, 155-156 DEET, 264, 267, 268, 275 Distal symmetric polyneuropathy (DSP)
From page 292...
... See also Chronic widespread pain interactions of multiple simultaneous exposures, 17 conclusions, 8, 178, 257 limitations of information, 17-18 diagnosis, 18, 41, 175, 178 External causes of mortality hospitalization studies, 175-176, 178, 179 conclusions, 8, 224, 257 multisymptom illnesses, 207 female veterans, 234 neurologic etiology, 121 intentional self-harm, 222, 223, 226 prevalence, 46, 175, 178 nerve-agent exposure and, 223, 225, 227 primary studies, 175-176, 179 primary studies, 221-223, 225-227 psychiatric comorbidities, 101 research recommendations, 9 secondary studies, 176, 178 secondary studies, 222, 223-224 symptoms, 175 suicides, 221, 223, 225, 226-227 updated and supplemental literature, 176-178 transportation accidents, 3-4, 8, 19, 221, 222, 223, Volume 4 summary, 19, 175-176 224, 225, 226, 227, 234 Fibrositis, 175 updated and supplemental literature, 222-224 Folliculitis, 164 Volume 4 summary, 3-4, 19, 221-222 Fort Devens and New Orleans Cohort Study, 44, 59-60 derivative studies, 44, 60 F mental and behavioral disorders, 102-103, 111 multisymptom illnesses, 210 Fatigue symptoms, 1, 46, 55, 103, 116, 118, 120, 123, reference study, 44, 59 124, 175, 210. See also Chronic fatigue syndrome Functional gastrointestinal disorders (FGID)
From page 293...
... See also Posttraumatic limitations of studies, 95 stress disorder; other specific disorders mental and behavioral disorders, 104, 112 anxiety disorders, 17, 19, 42, 50, 63, 99, 100, 101, multisymptom illnesses, 207-208, 218-219 102, 103-104, 105, 106, 107, 110, 111, 113, 114. musculoskeletal diseases, 170, 171, 172, 173-174 See also Generalized anxiety disorder; Obsessive neurological diseases, 128 compulsive disorder; Panic disorder; Posttraumatic stress disorder; Social phobia prevalence, 4, 61 chronic fatigue syndrome, 102 proportional morbidity ratios, 94 cognitive dysfunction, 101, 102 respiratory system diseases, 145, 146, 147, 151, 152, combat exposure and, 101, 102, 103-104, 105, 108, 153 114 skin diseases, 166-167 comorbidities, 19, 50, 101, 102, 107 Volume 4 summary, 19 conclusions, 8, 108-109, 256 Hypercholesterolemia, 135 disabled veterans, 106, 108-109, 113 Hypertension, 7, 135, 136, 138, 139, 140, 141, 144, 206, female veterans, 47, 106, 107, 229, 230, 231-232, 214 234 Hyperthyroidism, 91, 96 fibromyalgia, 101 Hypochondriasis, 99, 102 hospitalizations, 104, 112 Hypothalamic-pituitary-adrenal axis dysfunction, 154, mood disorders, 1, 19, 52, 99, 100, 106, 108, 115 160, 205, 211 116, 118, 119, 120.
From page 294...
... , 7, 19, 42, 44, 45, vaccination and, 51, 60 50, 52, 60, 157, 163, 206, 255, 271 Volume 4 summary, 19, 169 Multiple sclerosis (MS) Myasthenia gravis, 268 combat exposure and, 121 conclusions, 8, 125-126, 257 N female veterans, 231 latency, 8, 125 National Health Survey of Gulf War Veterans and Their mortality studies, 75, 125, 133 Families, 42, 45-48 pathogenesis, 124 derivative studies, 42, 46-48 primary study, 125, 133 diseases of the digestive system, 155, 157, 162 research recommendations, 9 mental and behavioral disorders, 102, 105, 107, 108, risk factors, 124-125 114 secondary study, 125 multisymptom illnesses, 206, 208-209, 211, 212 updated and supplemental literature, 125 reference study, 45-46 Multisymptom illnesses.
From page 295...
... See Pyridostigmine bromide reproductive outcomes, 199 Obesity, 92-93, 95, 135 respiratory symptom system diseases, 20, 47, 145, Obsessive-compulsive disorder, 99, 104 147, 148, 153 Oil-well fire smoke exposure signs and symptoms of toxic effects, 267, 269-270 blood and blood-forming organs, diseases of, 84, 87 Volume 4 summary, 20 cancer, 74, 75, 78 Nervous system diseases. See also Alzheimer's disease; chronic fatigue syndrome, 214 Amyotrophic lateral sclerosis; Multiple sclerosis; circulatory system diseases, 137, 142 Parkinson's; Peripheral neuropathy and myopathy; endocrine and metabolic diseases, 94, 98 other specific diseases extent of, 13-14, 17, 47, 229 brain injury and, 129 external causes of mortality, 53 chemical agent exposure and, 47, 59-60, 121, 133 genitourinary system diseases, 183, 184, 187 combat stress and, 125 modeling, 18, 32, 45, 46, 49, 50, 84, 94, 137, 142, environmental factors, 124-125, 129 146, 171, 184 factor-derived syndromes, 130-131 musculoskeletal diseases, 171, 173 female veterans, 230-231 reproductive outcomes, 192 genetic susceptibility, 44, 61, 129 respiratory system diseases, 4, 20, 42, 50, 55, 145, hospitalization studies, 128 146, 152-153 latency, 121, 125, 130 Operation Desert Shield, 1, 11, 13, 17 mortality studies, 125, 128, 129-130, 133 Operation Desert Storm, 1, 11, 13, 17 neuromuscular symptoms, 43, 52, 123, 210 Oregon and Washington Veteran Studies, 43-44, 57 neurotoxicant exposure and, 45, 47, 60, 122-123, derivative studies, 43-44, 57 128, 129, 130, 132 multisymptom illnesses, 274 pesticide/insecticide exposure and, 51, 55, 121, 122, Organophosphate-induced delayed polyneuropathy, 265, 123-124, 129, 133 268 pyridostigmine bromide and, 55, 121, 123-124 Organophosphates, 14, 18, 20, 60, 61, 78, 130, 266, 267, research recommendations, 9, 126, 261 268, 270 vaccines/vaccination and, 121, 123-124, 125, 133 Osteoarthritis, 171 Neurocognitive and neurobehavioral performance conclusions, 8, 118, 257 P deployment status and, 115, 117, 118, 119 derivative studies, 42, 43, 44, 48, 52, 56, 58-60 Pain.
From page 296...
... dysfunction borderline personality disorder and, 107-108 cohort study, 6 comorbidities, 102, 107-108, 111, 118, 154, 157, 163 female, 231 conclusions, 8, 256 male, 55-56 diagnosis, 99-100, 101, 102-103 Respiratory system diseases female veterans, 42, 47, 103, 106, 111, 231-232, 234 conclusions, 4, 8, 149, 257 multisymptom illnesses, 206, 207 deployment status and, 145-146, 147, 148-149, 150, personality and coping factors and, 63 151 predictors of, 103, 104, 107, 111 derivative studies, 42, 43, 47, 52, 53-54, 55 prevalence, 47, 50, 61, 62-63, 101, 102, 103, 104, female veterans, 230 106, 111, 112 hospitalization studies, 145, 146, 147, 151, 152, 153 POWs, 107, 114 mortality studies, 147, 148-149, 151, 153 sexual assault and harassment and, 42, 47 nerve agent exposure and, 20, 47, 145, 147, 148, 153 Volume 4 conclusions, 3, 19 oil-well fire smoke exposure and, 4, 20, 42, 50, 55, Pregnancy outcomes, adverse. See also Birth defects 145, 146, 152-153 conclusions, 8, 195, 257 pesticide exposure and, 51, 145 mood problems, 195 primary studies, 145-146, 147, 150-153 research recommendations, 10 prevalence, 47, 55-56, 61 secondary studies, 146-149 primary studies, 193, 201-202 updated and supplemental literature, 147-149 reference study, 51, 53-54, 61
From page 297...
... , 1, 12, 26, 31, 121 Volume 4 summary, 198 Skin diseases. See also specific disorders U cancer, 73, 76, 77, 78, 166 conclusions, 8, 167, 257 Ulcerative colitis, 155 disabled veterans, 164, 165, 168 United Kingdom Veterans Studies female veterans, 229, 230 chronic fatigue syndrome, 213-214 hospitalizations, 166-167 derivative studies, 42-43, 52-53, 54 neurobehavioral performance, 118, 120 diseases of the digestive system, 158-159 pesticide/insecticide exposure and, 56, 164 London School of Hygiene and Tropical Medicine, prevalence, 46, 57 43, 53-54, 90 primary studies, 164, 165, 167, 168 mental and behavioral disorders, 105, 113 secondary studies, 164, 165-167 multisymptom illnesses, 206, 209-210, 215, 217 smoke from burning waste or manure and, 56 reference studies, 51, 53-54 solvent exposure and, 164 University of London, 42-43, 51-53, 93, 119, 123, updated and supplemental literature, 165-167 132 vaccines and, 51 University of Manchester, 43, 53 Volume 4 summary, 3, 19, 164-165 Urinary tract infections, 180, 181 Sleep disturbance/disorder, 1, 10, 62, 99, 103, 106, 118, Urolithiasis, 180, 181 120, 175, 210, 230 US Agricultural Health Study, 270, 278 Small-fiber polyneuropathy, 124 US National Comorbidity Survey Replication, 100 Social phobia, 99 Utilization of health services, 42, 45, 50, 229.
From page 298...
... See also Female veteran health; Pregnancy outcomes troops deployed to Persian Gulf, 13, 228 World Health Organization (WHO) , 105 Wound healing, retarded, 165


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