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Final Report
Pages 1-8

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From page 1...
... To assist the research community, the National Academies' Human Embryonic Stem Cell Research Advisory Committee has conducted regional and other outreach meetings to help investigators and ESCRO committee members to interpret and implement the Guidelines.
From page 2...
... Specifically, the EO rescinded the previous policy that had restricted federal funding for hES cell research to in vitro work on lines derived before an earlier EO issued by President George W Bush, by stating "The Presidential statement of August 9, 2001, limiting Federal funding for research involving human embryonic stem cells, shall have no further effect as a statement of governmental policy." The EO issued by President Obama also called upon NIH to review its own existing guidance as well as other widely recognized guidelines on human stem cell research, including provisions establishing appropriate safeguards, and to develop and issue new NIH guidance for such research that is consistent with the EO's call to support "responsible, scientifically worthy" stem cell research.
From page 3...
... NIH has established a Working Group of the Advisory Committee to the Director of NIH to determine which hES cell lines were derived under conditions that meet the requirements of the NIH guidelines.2 It should be noted that the NIH guidelines prohibit the use of federal funding for research using hES cell lines derived from any source other than excess in vitro fertilization (IVF) embryos created for reproductive purposes.
From page 4...
... • hird, because the NIH guidelines only briefly address limits on the T research uses to which embryonic stem cell lines may be put, other guidelines will continue to be useful for a wider range of experiments with chimeras than those currently identified by NIH. To avoid complications, contradictions, and confusion, this Advisory Committee has developed an updated version of the National Academies' Guidelines that recognizes the new and increased influence of the NIH guidelines, and which incorporates references to the NIH guidelines as ap propriate in the text of the National Academies' Guidelines.
From page 5...
... THE FUTURE ROLE OF THE NATIONAL ACADEMIES IN STEM CELL RESEARCH OVERSIGHT In addition to reviewing the National Academies' Guidelines, the Advisory Committee also considered the future role of the National Academies 4 The resolution is available at
From page 6...
... ESCRO committees could also be helpful in assisting research institutions in monitoring developments in the field of stem cell research. In light of these comments, the Advisory Committee agrees that the continued use of ESCRO committees is useful, especially in circumstances where new hES cells are being derived.
From page 7...
... Some of these topics may have little to do with the Guidelines themselves, but might make excellent topics for future workshops or studies. In light of these discussions, the Advisory Committee decided that: • he Human Embryonic Stem Cell Research Advisory Committee T should prepare this brief final report communicating to the stem cell research community those elements of the National Academies' Guidelines that should remain in effect and under what conditions.


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