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Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases The Short-Term and Long-Term Outcomes: Workshop Report (2011) / Chapter Skim
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Pages 1-6

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From page 1...
... From a public health standpoint, the burden of disease is of growing concern, as is the incomplete understanding of the complex interactions of ticks, hosts, pathogens, and habitats that underlie changing disease patterns and the potential for climate change to exacerbate these trends. The Committee on Lyme Disease and Other Tick-Borne Diseases: The State of the Science was formed at the request of the National Institute of Allergy and Infectious Diseases to hold a 2-day workshop on the state of the science of Lyme disease and other TBDs.
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From page 2...
... These changes mean that people and animals interact at many more interfaces, creating new opportunities for the transmission of zoonotic pathogens, including those responsible for TBDs. This session examined the natural history of ticks and their wildlife and domestic hosts; outlined the contributions of animal health experts to understanding human TBD; explored genetic diversity among pathogens, vectors, and hosts; and showed how scientists are investigating the microbial community found within the ticks themselves.
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From page 3...
... The presenters discussed efforts to track the movement of pathogens in the environment, how infection moves from animals to people, and the burden of human infection and disease, especially among vulnerable populations. Some themes discussed included • The relative contributions of changes in surveillance, clinical recog nition, and testing patterns to the rising incidence of all of the major tick-borne diseases.
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From page 4...
... Ultimately, accurate diagnosis requires knowledge of the epidemiology and clinical manifestations, as well as specific and sensitive diagnostic tests. In this session, the presenters explored the limitations of existing tests for Lyme borreliosis and other tick-borne diseases, and they discussed promising new approaches to diagnostics that may improve the diagnosis of these diseases, and the challenges and needs for improving initial diagnosis.
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From page 5...
... A few of the themes discussed in this session included • Research and development of safe, effective, multipathogen human and animal vaccines for tick-transmitted diseases. • Land-use practices and public education as current tools to improve mitigation and prevention of TBDs.
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Key Terms

  • themes discussed
  • discussed included
  • session included
  • diagnostic tests
  • animal models

  • research gaps
  • individual speakers
  • committee invited
  • session focused
  • infectious diseases

  • infectious disease
  • research plan
  • animal health
  • translating research
  • presenters discussed

  • research based
  • lyme borreliosis
  • integrated research
  • major themes
  • advance research

  • gaps identified
  • persistence following
  • causative agent
  • major knowledge
  • initial diagnosis

  • tbd patients
  • laboratory findings
  • vitro laboratory
  • tbds begins
  • domestic hosts


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