Skip to main content

Currently Skimming:

1 Introduction and Background
Pages 17-36

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 17...
... ESTABLISHMENT AND HISTORY OF THE ARMED FORCES INSTITUTE OF PATHOLOGY AND THE JOINT PATHOLOGY CENTER The collection of biospecimens currently held by the JPC had its origins in the U.S. Civil War.
From page 18...
... . In recognition of that enlargement of mission, the institute was renamed the Armed Forces Institute
From page 19...
... 177) to facilitate the Armed Forces Institute of Pathology's (AFIP's)
From page 20...
... Mission: The JPC provides world class diagnostic subspecialty pathol ogy consultation, education and research services to federal agencies and operates the National Pathology Tissue Repository in support of the mission of the Department of Defense and other federal agencies. AFIP's civilian consultation mission was discontinued in September 2010, and the JPC took over from AFIP formal responsibility for accepting cases from the Military Health System and other federal government entities on April 1, 2011 (JPC, 2011)
From page 21...
... Box 1-1 cites some examples of how repository materials have been used to advance scientific knowledge. THE JOINT PATHOLOGY CENTER BIOREPOSITORY As of 2011, the JPC tissue repository comprised some 7.4 million accessions1 containing specimens or data from about 3.2 million people (Baker personal communication, 2011a)
From page 22...
... That research was of great importance in that it may provide clues for avoiding future influenza outbreaks. In 1995, a research team led by Jeffery Taubenberger, chief of the Division of Molecular Pathology of the Armed Forces Institute of Pathology (AFIP)
From page 23...
... sent to the repository. In recent decades, information accompanying most accessions in the Central Collection includes patient name, Social Security number,3 date of birth, repository accession number, surgical number, type of specimen, contributor's4 health care facility, and specialty branch num 3Social Security numbers were first assigned in late 1936 (Social Security Administration, 2012)
From page 24...
... It usually includes patient name, facility where the specimen originated, surgical number, and diagnosis (Baker personal communication, 2011a)
From page 25...
... d. Pathology consultation records contain individually identifiable health information.
From page 26...
... It noted that the mission of the center includes support of two primary collections -- the pathology material accumulated by AFIP in the course of its clinical, education, and research activities (the Central Collection) and pathology material from DoD military treatment facilities closed under the BRAC program (the BRAC Collection)
From page 27...
... · What considerations should be given to utilization for research of unique, one-of-a-kind, material within the Central Collection of the tissue repository? · What existing or emerging technologies (either as an intrinsic func tion or through partnership)
From page 28...
... EARLIER REPORTS ADDRESSING ARMED FORCES INSTITUTE OF PATHOLOGY AND JOINT PATHOLOGY CENTER OPERATIONS Four outside reviews of the tissue repository's operation have been conducted since the BRAC Commission recommendation for disestablishment was promulgated. Salient results of the reviews are summarized below.
From page 29...
... Asterand's examination of the utility of Central Collection specimens for research purposes yielded mixed results. Over 50 percent of sampled cases had tumor (primary, metastatic, or both)
From page 30...
... . The BRAC Collection of materials, consisting of medical records and tissue specimens transferred to the repository for storage and maintenance from closed military health facilities, were evaluated separately.
From page 31...
... Its most conservative estimate -- based on the current state of the collection, accessibility of the materials to requesting parties without restriction, and the provision of complete tissue blocks (that is, without preser vation of any portion for future use) -- was about $1.4 billion.6 The report concluded that "the greatest strengths of the Central Repository for research and educational purposes lie in the breadth and depth of its materials and in the potential for developing cohorts for rare and unusual diseases" but that both it and the BRAC Collection "are in need of better data organization and enrichment of patient clinical information (particularly follow-up)
From page 32...
... assessed whether the HIPAA Privacy Rule was having an effect on health research and offered recommendations to promote efficient health research while maintaining the privacy of personally identifiable health information. The report stated that the Privacy Rule did not protect privacy as well as it should and that it was hindering effec
From page 33...
... It concludes with a discussion of the scientific and technical limitations on using in research samples that were originally obtained for pathology purposes. Legal, ethical, and regulatory considerations regarding the use of repository specimens in clinical care, education, and research activities are taken up in Chapter 3.
From page 34...
... April 21, 2011 presentation to the Committee on the Appropriate Use of the Armed Forces Institute of Pathology's Tissue Reposi tory Follow ing Its Transfer to the Joint Pathology Center. Washington, DC: Institute of Medicine.
From page 35...
... 2012. Property and intellectual property considerations affecting the Armed Forces Institute of Pathology's Tissue repository following its transfer to the Joint Pathol ogy Center.
From page 36...
... The Armed Forces Institute of Pathology, 1862­2011. http://www.bordeninstitute.army.mil/other_pub/loe.html (accessed December 28, 2011)


This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More information on Chapter Skim is available.