Transforming Glycoscience A Roadmap for the Future (2012) / Chapter Skim
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2 The Landscape of Current Research in Glycoscience
2 The Landscape of Current Research in Glycoscience
Pages 29-36
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From page 29... ...
and international glycoscience efforts, the committee reviewed information provided to it by federal sponsors,1 received community input through its website and through a workshop held in January 2012,2 gained additional perspectives through further data-gathering efforts,3 1 Representatives of the National Institutes of Health (NIH) , Food and Drug Administration (FDA)
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5 The background paper was prepared at the request of NIH, which asked the NRC to reach out to researchers and federal program managers for their views on the state of glycomics and glycoscience and challenges facing the field, in order to better understand how to frame the design of the current study. The paper summarizes information received during this outreach, in which NRC staff and a small group of glycoscience experts spoke with approximately 40 scientists and program managers from government, academia, and industry.
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FIGURE 2-1 Glycoscience research spans a diversity of fields, as indicated by the Web of Science subject categories associated with published research. Results from the WOS citation search described above were sorted by WOS subject category, and the top 20 subject areas are depicted above.
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The size of the bubbles represents the relative proportion of glycoscience papers published. Underlying world map adapted from David Niblack.
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From page 33... ...
Other scientific forums include the biennial Charles Warren workshops on glycoscience characterization and analysis and the Beilstein Symposia on Glyco-Bioinformatics. 2.2 AN "OMICS" FIELD -- GLYCOSCIENCE IN ITS INFANCY The citation search in the WOS database undertaken by the committee was intended to be broad so as to include research on cellulose and other carbohydrate polymers as well as glycoconjugates.
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It is beyond the committee's charge to propose a similar formal glycoscience initiative comparable to that of the Human Genome Project or the National Nanotechnology Initiative. Rather, the committee seeks to describe the current status of the field of glycoscience and explore its potential, while clearly recognizing that advancing the field in a similar dramatic fashion, as with genetics and genomics, would require engagement by and the efforts of multiple stakeholders beyond the current community of glycoscience specialists.
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Because glycoscience provides a level of data that can build from and complement genomic and proteomic information, inclusion of glycoscience components in international Human Genome Organization (HUGO) and Human Proteome Organization (HUPO)
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2.4CONCLUSION The landscape of glycoscience research provides a picture of a global field with a range of ongoing research efforts, both academic and commercial, and one for which the community sees significant opportunities as well as common challenges. The following chapters of this report attempt to present a holistic view of glycoscience's contributions to critical areas such as human health, energy, and materials science; to bring new attention from both experts and nonexperts to the field; and to point the way toward a roadmap and a vision for the future of the field.
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