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3 Methods
Pages 29-36

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From page 29...
... For that review, the committee relied on current evidence-based clinical practice guidelines from government and scientific organizations and existing systematic reviews, rather than conduct a de novo evaluation of the primary literature. Managing patients who have CMI involves more than administering a therapy.
From page 30...
... . Databases of clinical trials (Congressionally Directed Medical Research Programs, DeployMed ResearchLINK, BioMed Central current controlled trials, International Federation of Pharmaceutical Manu­ acturers f and Associations clinical-trials portal, Thomson CenterWatch Clinical Trials Listing Service, UK Clinical Research Network Study Portfolio, US National Institutes of Health's ClinicalTrials.gov, and World Health Organization International Clinical Trials Registry Platform Search Portal)
From page 31...
... After the title and abstract screen, two reviewers independently screened the references remaining by using the full-text articles. In addition to the eligibility criteria applied during the title and abstract screen, they excluded citations at this level that were only meeting abstracts, that were systematic reviews that had been updated, or that described only study protocols but had no results.
From page 32...
... The committee believes that symptoms shared by CMI and the other conditions may respond similarly to approaches to symptom management. Twelve commonly comorbid conditions or conditions with shared symptoms were identified: fibromyalgia, chronic pain, CFS, somatic symptom disorders, sleep disorders, functional gastrointestinal disorders, depression, anxiety, posttraumatic stress disorder, traumatic brain injury, substance use and addictive disorders, and self-harm.
From page 33...
... aMEDLINE accessed via PubMed. NOTE: ACP = American College of Physicians; CENTRAL = Cochrane Central Figure 3-1 Register of Controlled Trials; CFS = chronic fatigue syndrome; CINAHL = Cumulative Index to Nursing and Allied Health Literature; DARE = Database of Abstracts ­ of Reviews of Effectiveness; EMBASE = Excerpta Medica database; IBS = irritable bowel syndrome.
From page 34...
... Three meetings open to the public were held to hear from invited speakers. Presentation topics included general information on CMI, current practices and capabilities in the Veterans Health Administration, current understanding of the underlying mechanism of CMI, treatments for CMI, and how health information technology is being used in managing chronic conditions.
From page 35...
... CURRENT RESEARCH ON CHRONIC MULTISYMPTOM ILLNESS As part of its information gathering, the committee searched clinicaltrial databases (Congressionally Directed Medical Research Programs, DeployMed ResearchLINK, BioMed Central current controlled trials, International Federation of Pharmaceutical Manufacturers and Associations clinical-trials portal, Thomson CenterWatch Clinical Trials Listing Service, UK Clinical Research Network Study Portfolio, US National Institutes of Health's ClinicalTrials.gov, and World Health Organization International Clinical Trials Registry Platform Search Portal) and identified a number of current research projects on CMI treatments.


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