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Field Testing Genetically Modified Organisms Framework for Decisions (1989) / Chapter Skim
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11 Conclusions and Recommendations: Microorganisms
Pages 123-132

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From page 123...
... In many respects, molecular methods resemble the classical methods for modifying particular strains of microorganisms, but many of the new methods have two features that make them even more useful than the classical methods. Precision allows scientists to make genetic modifications in ~n~crobial strains that can be cha~acter~zed more fully, in some cases to the level of the DNA sequence.
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From page 124...
... Questions concerning the effects of an introduced microorganism arise whenever the intended introduction differs substantially from those with an established record of safety. Such questions as unintended persistence and possible adverse effects should be addressed scientifically, and as the scientific community continues to accumulate information regarding the safety or risk of environmental applications of microorganisms in field tests, levels of oversight can be tuned to the needs of particular situations.
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From page 125...
... 11-1~. The high uncertainty status implies that potential adverse effects exist and are coupled with potential inability to control the microorganism, and hence its potential effects.
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From page 130...
... 130 Q o o ~._ cut ~ ^ cut 0 _ a' ~ E4, ~n~ n ,,: wc a, ~ 4,, as w 0~ 0 ~ m.> ~ ~ o)
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From page 131...
... As the agencies grant permission to introduce genetically modified microorganisms in field tests, they will receive advice Dom panels of experts who can utilize the decision framework described here. With experience, familiarity wiD increase, and we anticipate this will be accompanied by adjustments in the rigor of oversight.
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  • dom panels
  • underlying variables
  • laboratory experunentation
  • prior introductions
  • receive advice

  • toxic podut
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  • introduction differs
  • risk categories
  • microorganisms intended
  • established practice
  • specific numerical


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