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Clinical Practice Guidelines Directions for a New Program (1990) / Chapter Skim
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Pages 135-135

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From page 135...
... Further, established risk factors are present in less than one-quarter of women with breast cancer, so that a screening program restricted to high-risk groups is likely to miss the majority of cases. Retrospective studies of the effectiveness of BSE have produced mixed results, and BSE has not been studied in a prospective controlled trial with mortality as an outcome.8 A recent meta-analysis of pooled data from 12 studies found that women who practiced BSE before their illness were less likely to have a tumor of 2.0 cm or more in diameter or to have evidence of extension to lymph nodes.36 The studies from which these data were obtained, however, suffer from important design limitations and provide little information on clinical outcome (e.g., breast cancer mortality)
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Key Terms

  • breast cancer
  • clinical examination
  • screening program
  • cancer mortality
  • risk factors

  • clinical breast
  • breast examination
  • annual clinical
  • insufficient evidence
  • american cancer

  • regular clinical
  • canadian task
  • cancer society


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