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5 Risk Characterization
Pages 148-154

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From page 148...
... that includes discussion of data gaps, lack of knowledge, natural variability, and other factors that might influence confidence in the risk estimate. The discussion can be viewed as a weight-of-evidence description in which the strengths and weaknesses of each assumption and each type of data used in the risk assessment are discussed.
From page 149...
... In biological opinions on salmon, the National Marine Fisheries Service appears to favor a probabilistic approach that is based on population modeling. The Fish and Wildlife Service seems not to use a quantitative approach, either concentration-ratio or probabilistic, for risk characterization.
From page 150...
... Ultimately, decision-makers are provided with a risk estimate that reflects the probability of exposure to a range of pesticide concentrations and the magnitude of an adverse effect (if any) to the exposures that answers the fundamental question, What is the probability that registration of this pesticide will lead to a specified adverse effect on a listed species or its critical habitat?
From page 151...
... . The committee recognizes the pragmatic demands of the pesticide registration process and encourages EPA and the Services to consider probabilistic methods that have already been successfully applied to pesticide risk assessments (Odenkirchen 2003 [EPA's Terrestrial Investigation Model v 2.0]
From page 152...
...  A number of existing probabilistic methods have been shown to be applicable and practical for ecological risk assessments that involve pesticides.  The transition from concentration-ratio to probabilistic approaches can begin now, starting with simple registrations, focusing on a small set of sensitive key parameters, and drawing on the considerable literature and guidance on probabilistic approaches.
From page 153...
... 2002. Threshold models for species sensitivity distributions applied to aquatic risk assessment for zinc.
From page 154...
... 2001. Methodology for aquatic ecological risk assessment.


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