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The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences (2014) / Chapter Skim
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13 Creating an Evidence-Based Blueprint for Action
Pages 137-142

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From page 137...
... Becerra, Associate Professor, Department of Global Health and Social Medicine, Harvard Medical School, and Qian Gao, Professor, Shanghai Medical College, Fudan University, China.
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From page 138...
... Becerra and Gao listed several potential action items and resource needs that could help expose and address the "silent epidemic" of DR TB in children: • Children with DR TB can be a key indicator to help guide a large scale policy response. The identification of children with DR TB allows for the monitoring of gaps, needed drugs, and whether programs are accessing the support they need to deliver care to children.
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From page 139...
... • The roles of microscopy, microbial culture, and molecular testing should be evaluated and optimized to allow for sensitive, specific, and timely detection of MDR and XDR TB. • A central body should be in charge of the entire laboratory net work, including private laboratories.
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From page 140...
... • Routine active case finding through cough surveillance of all hos pital admissions and other means is an effective approach to trans mission control, especially if combined with molecular rapid testing for TB and for MDR TB. To stem transmission, cough detection needs to progress to diagnosis and effective therapy within a matter of days, not months.
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From page 141...
... In addition, new and more capable molecular diagnostics could greatly speed up diagnosis, which would be "a tremendous stride forward." Bloom noted that these principles reinforce the need for basic, developmental, and operational research. Bloom offered the following proposals for next steps: • The most limiting factor in the supply of drugs is a lack of infor mation.
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From page 142...
... Public–private partnerships could be a way to make expertise in the private sector available to the public sector. Bloom also observed that successful community-based care of MDR TB patients, such as that implemented in South Africa and elsewhere, is very promising and could be generalized to many other countries.
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Key Terms

  • tuberculosis reference
  • lixin zhang
  • yanlin zhao
  • supranational tuberculosis
  • qian gao

  • drug discovery
  • swedish institute
  • diagnostic tests
  • laboratory networks
  • china cdc

  • fudan university
  • communicable disease
  • global awareness
  • chinese academy
  • sciences key

  • inaugural director
  • pathogenic microbiology
  • sven hoffner
  • global health
  • key laboratory

  • shanghai medical
  • discovery center
  • harvard school
  • medical college
  • care workers

  • drug resistance
  • hiv epidemic
  • tive settings
  • studies using
  • vice throughout


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