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1 Introduction
Pages 17-27

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From page 17...
... There is now greater understanding of the dynamic behavior of ENMs; minimum characterization standards, which are still evolving, are now more widely accepted by the field; some reference materials have been distributed and evaluated with models; models for estimating environmental exposures to ENMs have been proposed; and methods for characterizing ENMs in relevant matrices have been developed. However, research on the potential EHS implications of ENMs still lacks context, particularly with regard to future risks, because materials and their uses are changing rapidly.
From page 18...
... STUDY SCOPE The US Environmental Protection Agency (EPA) requested that the National Research Council perform an independent study to develop and monitor the implementation of an integrated strategy for research on EHS aspects of ENMs (see Appendix B for complete statement of task)
From page 19...
... In addition to the conceptual framework and the gaps and tools, the committee identified four broad high-priority research topics that formed the backbone of its proposed research strategy. The committee recognized the evolving nature of ENM research and, in selecting the four broad categories, envisioned a risk-based system that would be informed and shaped by research outcomes and would support approaches to environmental and human-health protection.
From page 20...
... , in response to ENMs; and assessment of the effects of ENMs on endocrine and developmental systems of organisms.  "Adaptive research and knowledge infrastructure for accelerating research progress and providing rapid feedback to advance research.
From page 21...
... Mechanisms identified for implementation included fostering interagency interaction, collaboration, and accountability; developing and implementing mechanisms for stakeholder engagement; advancing integration among sectors and institutions involved in EHS research, such as public–private partnerships; and structural changes that address conflicts of interest. In considering its task, the committee developed indicators that would serve as criteria for gauging the extent of research and implementation progress in this second report (see Boxes 1-1 and 1-2 for summaries of indicators of research and implementation progress, respectively)
From page 22...
...  Identifying critical populations or systems exposed.  Characterizing released materials and associated receptor environments.
From page 23...
... Managing potential conflicts of interest  Progress toward achieving a clear separation in management and budgetary authority and accountability between the functions of developing and promoting applications of nanotechnology and understanding and assessing its potential health and environmental implications.  Continued separate tracking and reporting of EHS research activities and funding distinct from those for other, more basic or application-oriented research.
From page 24...
... and helps to develop a framework for coordination among federal agencies and mechanisms to support implementation of the strategy. The committee's original charge to develop and monitor implementation of a research strategy was written in the absence of the 2011 federal EHS research strategy.
From page 25...
... that complements Figure 1-1 and provides a vision for the EHS nanotechnology research enterprise. Figure 1-2 describes the interrelated and interdependent research activities that are driven by ENM production and highlights the importance of a coordinated research infrastructure.
From page 26...
... Nanotechnology Environmental Health Implications Working Group, Na noscale Science, Engineering, and Technology Subcommittee, Committee on Technology, National Science and Technology Council. September 2006 [online]
From page 27...
... National Nanotechnology Initiative. Nanotechnology Environmental Health Impli cations Working Group, Subcommittee on Nanoscale Science, Engineering, and Technology, Committee on Technology, National Science and Technology Coun cil.


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