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Biotechnology An Industry Comes of Age (1986) / Chapter Skim
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Pages 117-121

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From page 117...
... , 45-48 Adhesives, 15, 21 Agency for International Development, 79, 110 Agriculture, see Genetic engineering, agricultural; specific crops and plants Agrobacterium tumefaciens, 35, 36, 40 AIDS, see Acquired immune deficiency syndrome Alexander, Martin, 54, 55-60 Amino acids, 5, 15, 18, 20, 37, 94 See also Proteins Anderson, W French, 43, 45-48, 51-52 Animals, see Genetic engineering, animals; specific animals Antibiotics, 1, 5, 14, 21, 30, 35, 95 Antibodies, 5, 14, 20, 73 See also Monoclonal antibodies Antigens, 25-26 Asilomar conference, see International Conference on Recombinant DNA Molecules Atherosclerosis, 52, 89 B B lymphocytes, 25, 27 Bacillus thuringiensis, 34 Bacteria, 1, 3, 11, 15-17, 20-21, 24, 28, 32, 33, 59, 66, 71, 95 See also specific bacteria Bentley, Orville G., 64, 78 Beta-thalassemia, 43, 45 Biological synthesis, 14 Biologics, 13, 72-75, 78, 82, 115 Biotechnology firms challenges to, 89-90 characteristics, 85-87 funding, 39, 85-87, 111-112 importance of in United States, 111 successful, 87-89 types, 10, 12-13, 84-85 See also Industry Bone marrow cells, 45-48 Cabinet Council on Natural Resources and the Environment, 79 Cabinet Council Working Group on Biotechnology, 49, 79-81 Cancer, 19, 28, 89 Cattle, 30, 31, 40, 41 Cells bone marrow, 45-48 cloning, 3, 5, 27 culture techniques, 34 fermentation, 5, 22-24 fusion, 25, 75 germline, 7, 49-51, 52 growth, 24 hosts, 17, 34-35 molecular machinery, 15-18, 19, 22 sexual reproduction, 6-7 somatic, 7, 44-50 transformed, 47 tumor, 28, 29, 36 university-industry research, 103, 104 See also DNA; Genes; Human gene therapy; Recombinant DNA Centers for Disease Control, 79 Centocor, Inc., 87-90 Cetus, 86, 90 Chemicals, 4, 5, 9, 16.
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From page 118...
... 57, 65-67, 69-71 H Handler, Philip, 64 Harsanyi, Zsolt, 64, 83 Health care, 6, 14, 19, 20, 48, 87-89 Healy, Bernadine, 64, 70, 80-81 Hemophilia, 45 Hepatitis, 20, 28, 89 Herbicides, 38, 59 Herpes, 20, 28 High-performance liquid chromatography, 23 Homeostasis, 68 Hormones, 4, 14, 15, 16, 18, 30, 31, 34, 40, 93 See also Growth hormones House sparrows, 55 Human gene therapy clinical trials, 70 development, 4, 43-44, 73, 81 enhancement of traits, 51-53 germline gene therapy, 7. 49-51, 52 legislation, 82 somatic cell gene therapy, 7, 44-50 Human insulin, 18 Human serum albumin, 19 Hybrid-myeloma ("hybridoma")
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From page 119...
... , 50, 72-73 J Jaenisch, Rudolf, 30, 39-41 Japan basic and applied research, 113-114 competition with United States, 12-13, 107-116 funding of biotechnology, 111-112 government support for biotechnology, 108109, 110 patents, 113 regulation of biotechnology, 112 start-up firms, 111 technology transfer, 114-115 trained personnel, 113-114 Jaworski, Ernest G., 31, 34-35 Johnson, Irving S., 64, 81, 107-109, 115-116 K Karny, Geoffrey M., 64, 77-78, 79 Kipnis, David M., 98, 101-105 Klebsiella pneumoniae, 32 Kohler, Georges, 27 Leder, Philip, 2. 4, 14, 16, 30, 42 Legislation of biotechnology, see Research, regulation, and legislation of biotechnology; specific legislation Legumes, 32, 37 Lesch-Nyhan disease, 45-46 Licensing agreements, 86 Livestock, 1,31,37,51, 55 Lymphokines, 19, 74 M Molecular products of biotechnology, 4-5, 14-29 Monoclonal antibodies, 5, 25-29, 31, 72, 73, 85, 87-89, 115 Monsanto-Washington University agreement, 101-105 Moore, John A., 64, 76 Multiplication of genetically engineered organisms, 58-59 Multiproduct firms, 84 Muscular dystrophy, 45 N Nakasone, Yasuhiro, 108-109 Nathans, Daniel, 54 National Academy of Sciences Forum on Research with Recombinant DNA, 66, 67 National Bureau of Standards, 79 National Environmental Protection Act (NEPA)
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From page 120...
... government biotechnology research, regulation, and legislation, 4, 9-10, 39, 62-63, 64-83, 109-111, 112 commercialization of biotechnology, 109-115 competition in biotechnology, 115-116 funding of research in biotechnology, 109-111 patent laws, 92-95 See also United States; specific government agencies Vaccines, 3, 5, 6, 14, 20, 31, 74 See also specific vaccines Vectors, genetically engineered, 16-17, 35, 95 Venereal diseases, detecting and monitoring, 28 Vitamins, 1, 5, 15, 21, 93 W Rabbit globin gene, 40 Rabies. 31 RAC, see Recombinant DNA Advisory Committee R&D limited partnership funding.
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Key Terms

  • gene therapy
  • genetically engineered
  • human gene
  • genetic engineering
  • dna molecules

  • university agreement
  • engineered organisms
  • monoclonal antibodies
  • cell gene
  • specific crops

  • specific government
  • dna advisory
  • deficiency syndrome
  • cabinet council
  • asilomar conference

  • acquired immune
  • house office
  • growth hormones
  • genetic information
  • immune deficiency

  • somatic cell
  • biotechnology firms
  • occupational safety
  • amino acids
  • trade secrets

  • bone marrow
  • dna bans
  • shope papilloma
  • plants plasmids
  • liquid chromatography


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