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Drug Repurposing and Repositioning Workshop Summary (2014) / Chapter Skim
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References
Pages 57-64

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 57...
... : A scientific approach to off-label treatment options for people with ALS using tweets and twitters. Amyotrophic Lateral Sclerosis 10(3)
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From page 58...
... 2007. Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.
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From page 59...
... 2013. GSK announces top-line results from pivotal Phase III study of darapladib in chronic coronary heart disease.
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From page 60...
... 2011. Noncanonical TGFbeta signaling contributes to aortic aneurysm progression in Marfan syndrome mice.
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From page 61...
... 2011b. Associating drugs, targets and clinical outcomes into an integrated network affords a new platform for computer-aided drug repurposing.
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From page 62...
... 2012. Drug repurposing: Finding new uses for approved drugs and shelved drug candidates is gaining steam as a pharmaceutical development strategy.
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From page 63...
... 2012. Targeting the transposase domain of the DNA repair component metnase to enhance chemotherapy.
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Key Terms

  • drug repurposing
  • marfan syndrome
  • accessed february
  • amyotrophic lateral
  • drug discovery

  • reviews drug
  • lateral sclerosis
  • kinase inhibitor
  • translational medicine
  • science translational

  • aortic aneurysm
  • nature reviews
  • computational drug
  • blockade attenuates
  • approved drugs

  • shelved drug
  • multiple myopathic
  • obese gene
  • refractory multiple
  • receptor blockade

  • gene encoding
  • indications using
  • mouse obese
  • heart network
  • leptin deficiency

  • existing drugs
  • aortic root
  • drugs enabling
  • rare disease
  • congenital leptin


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