Acute Exposure Guideline Levels for Selected Airborne Chemicals Volume 17 (2014) / Chapter Skim
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Pages 458-474
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9 Boron Tribromide1 Acute Exposure Guideline Levels PREFACE Under the authority of the Federal Advisory Committee Act (FACA)
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Boron Tribromide 459 effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure.
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460 Acute Exposure Guideline Levels TABLE 9-1 AEGL Values for Boron Tribromide Classification 10 min 30 min 1h 4h 8h End Pointa AEGL-1 0.33 ppm 0.33 ppm 0.33 ppm 0.33 ppm 0.33 ppm Analogy with (nondisabling) (3.4 (3.4 (3.4 (3.4 (3.4 hydrogen bromide mg/m3)
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Boron Tribromide 461 level of odor awareness. Boron tribromide is considered irritating to the skin and mucus membranes and corrosive to the eyes (HSDB 2013)
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462 Acute Exposure Guideline Levels Although the inhalation toxicity of boron oxide and borates is well established (ATSDR 2010) , no information on the inhalation toxicity of boric acid in humans was found.
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Boron Tribromide 463 Moderate to severe fibrinonecrotic rhinitis was observed only in the anterior most region of the nasal passages. The same authors (Kusewitt et al.
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464 Acute Exposure Guideline Levels TABLE 9-4 One-Hour Inhalation Studies of Hydrogen Bromide Species Concentration (ppm) Mortality Ratio Rat 2,205 1/10 2,328 4/10 2,759 4/10 3,253 6/10 3,711 7/10 3,822 10/10 Mouse 507 0/10 875 7/10 1,036 9/10 1,163 10/10 Source: Adapted from McEwen and Vernot 1972.
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Boron Tribromide 465 hydrogen halides, such as hydrogen fluoride and hydrogen chloride, the mouse is more susceptible than the rat to the lethal effects (NRC 1991)
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466 Acute Exposure Guideline Levels 6.
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Boron Tribromide 467 TABLE 9-7 AEGL-2 Values for Boron Tribromide 10 min 30 min 1h 4h 8h 83 ppm 28 ppm 13 ppm 3.3 ppm 1.7 ppm (850 mg/m3)
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468 Acute Exposure Guideline Levels TABLE 9-9 AEGL Values for Boron Tribromide Exposure Duration Classification 10 min 30 min 1h 4h 8h AEGL-1 0.33 ppm 0.33 ppm 0.33 ppm 0.33 ppm 0.33 ppm (nondisabling)
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Boron Tribromide 469 ACGIH (American Conference of Governmental Industrial Hygienists)
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470 Acute Exposure Guideline Levels Kusewitt, D.F., D.M. Stavert, G
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Boron Tribromide 471 Wong, L.C., M.D. Heimbach, D.R.
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472 Acute Exposure Guideline Levels APPENDIX A DERIVATION OF AEGL VALUES FOR BORON TRIBROMIDE Derivation of AEGL-1 Values Inadequate data were available on boron tribromide, so AEGL-1 values were based on the AEGL-1 values for hydrogen bromide. Calculation: On the basis that one mole of boron tribromide hydrolyzes into three moles of hydrogen bromide, the hydrogen bromide AEGL-1 value was divided by 3.
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Boron Tribromide 473 1-h AEGL-3 120 ppm ÷ 3 = 40 ppm 4-h AEGL-3: 31 ppm ÷ 3 = 10 ppm 8-h AEGL-3: 15 ppm ÷ 3 = 5 ppm
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474 Acute Exposure Guideline Levels APPENDIX B ACUTE EXPOSURE GUIDELINE LEVELS FOR BORON TRIBROMIDE Derivation Summary AEGL-1 VALUES 10min 30 min 1h 4h 8h 0.33 ppm 0.33 ppm 0.33 ppm 0.33 ppm 0.33 ppm Data adequacy: Inadequate data were available on boron tribromide, so values were based on the AEGL-1 values for hydrogen bromide. On the basis that one mole of boron tribromide hydrolyzes into three moles of hydrogen bromide, the hydrogen bromide AEGL-1 values were divided by 3.
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