Skip to main content

Review of the Formaldehyde Assessment in the National Toxicology Program 12th Report on Carcinogens (2014) / Chapter Skim
Currently Skimming:

Appendix D: Literature-Search Strategies Completed in Support of the Committee's Independent Assessment of Formaldehyde
Pages 199-206

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 199...
... The search strategies, exclusion strategies, and number of resulting studies are described below. CANCER STUDIES IN HUMANS The committee established exclusion criteria and a literature-search strategy to identify studies in humans (Box D-1)
Read the entire page →
From page 200...
... representing the results is depicted in Figure D-2. A committee member and National Research Council staff independently screened the titles for potential papers reporting on animal cancer bioassays.
Read the entire page →
From page 201...
... T The literatu ure tree in Figu ure D-3 shows how the initiaal search resultts were narrow wed down to t 83 publicatiions by Nation nal Research CCouncil staff uusing publicatiion titles and a abstracts.. The remain ning publicatioons were evaaluated by tw wo committee members using the titlles, abstracts, and full text..
Read the entire page →
From page 202...
...  The publication was already cited in the s ubstance profiile for formalde e hyd de in the Nation nal Toxicology Program 12th Report on Carrcinogens.  The publicationn did not includ de primary dataa.
Read the entire page →
From page 203...
... Immune Effects The committee conducted two literature searches to identify recent studies pertaining to immune effects after exposure to formaldehyde (see Box D-4)
Read the entire page →
From page 204...
... 204 FIGURE D-3 Literature tree for genotoxicity searcch. See Box D-3 for a description of the ex xclusion criteria and search strategy.
Read the entire page →
From page 205...
... Research Council staff identified 46 studies that contributed an understanding of hematologic effects related to formaldehyde exposure of humans, animals, and isolated hematologic cell types (see Table 3-18)
Read the entire page →
From page 206...
... FIGUR RE D-4 Literaturre tree for immun ne-effects searchh. See Box D-4 ffor a descriptionn of the excllusion criteria an nd search strategy.
Read the entire page →

Key Terms

  • search strategy
  • exclusion criteria
  • immune effects
  • council staff
  • literaturre tree

  • toxicology program
  • formald dehyde
  • experimental animals
  • national toxicology
  • unscheduled dna

  • literature searches
  • hematologic effects
  • primary data
  • identify studies
  • effects related

  • animal cancer
  • initiaal search
  • exposed experimental
  • mechanisttic evidence
  • identify anda

  • bioassays yielded
  • animal carcinogenicity
  • research ccouncil
  • studies pertaining
  • search strategies

  • search term
  • committee conducted
  • carcinogenicity bioassays
  • recently publish
  • established exclusion


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.