Responsible Science Ensuring the Integrity of the Research Process: Volume II (1993) / Chapter Skim
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11 Report of the Committee on Academic Responsibility
11 Report of the Committee on Academic Responsibility
Pages 206-222
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From page 206... ...
...overseeing He work done by staff, research fellows, and residents, to assure Cat each has the knowledge, information, and skills necessary to meet BTRC standards. NOTE: These are developing guidelines, a working document reflecting the standards of the faculty of the BTRC, the Department of Neurological Surgery, and the School of Medicine, University of California, San Francisco.
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From page 207... ...
§3.~.2 The PI has final responsibility for maintaining methodology notebooks and laboratory master logs relevant to the PI's laboratory and for seeing to it that those books
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From page 208... ...
§3.~.4In some laboratories, a "data manager" at UCSF usually a staff research associate or specialist designated by and responsible to the PI may maintain methodology notebooks, oversee experimental notebooks, have laboratory management responsibilities, and/or instruct new fellows and residents in laboratory techniques and protocols. In such laboratories, PIs meet with their data manager to review research progress and data at least once each month (see §3.~.6~.
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to have them moved to the UCSF storage facility at Oyster Point; the BTRC administrative office keeps a record of retrieval information. §4 Standards for BTRC Databooks §4.
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This central log, a hardbound databook with consecutively numbered pages, should contain: - the titles of the studies done by everyone in the laboratory, the investigators' names, the inclusive dates of the experiments, and - the location of the experimental notebook and any raw data, computer files, or other relevant materials stored separately for each logged experiment. §4.3 Methodology Notebook §4.3.!
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From page 211... ...
. §4.3.2 The methodology notebook is the final and absolute arbitrating reference when questions of technique are raised in the context of the educational and training responsibilities of Me BTRC.
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From page 212... ...
A Specific notes about special procedures or steps that differ from the techniques specified in the methodology notebook (e.g., changes in incubation time or temperature, concentration of trypsin, tumor cell inoculum, infusion rates, anesthetic procedure)
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. Raw data include, but are not limited to, - handwritten notes on, e.g., cell or colony counts, tumor dimensions, physiologic endpoints, daily observations on animals, or other visually measured data (e.g., CT or NMR tapes)
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From page 214... ...
§4.4.7.3 Data are recorded chronologically as they are collected on consecutive pages of the experimental notebook. §4.4.7.4 Entries should be organized in such a way that someone not familiar with the specific experiment recorded can retrieve all the pertinent details of the study, from the hypothesis to the published article.
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From page 215... ...
§4.5 Data Selection File Manuscript preparation involves the selection of specific experimental data from the experimental notebook.
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From page 216... ...
Any other material considered pertinent to selection of data, to authorship, or to any substantial related matter arising during the development of the paper. §4.5.3 At the completion of a research project, the data selection file for each paper developed from the project is archived in the BTRC together with the experimental notebooks for the project and the photocopies of the relevant material from the methodology notebooks.
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From page 217... ...
§5.2.2.2 If the first author leaves the BTRC before the data selection file is complete, responsibility for maintaining it reverts to the senior author. §5.2.3 The first and senior authors jointly decide whether or not another participant is to be a coauthor.
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From page 218... ...
One copy of the form is included in the data selection file and one in the manuscript files All coauthors must personally sign this form (or a copy, see 7.4.2~. Signatures in absentia are never legally acceptable.
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From page 219... ...
§7.4.3 The paper is submitted after all coauthors' signatures are obtained. §7.4.4 When, aider journal peer review, revision of a paper involves additional or different data, a substantial revision of conclusions, a change in authorship, or a change in order of authorship, the renewed agreement of all coauthors is documented on a new Author's Agreement form.
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From page 220... ...
.read original sources in Heir entirety .photocopy references or log complete and accurate citation Plan experimental study design .obtain statistical consultation .review and photocopy relevant sections from the appropriate methodology notebook for reference In the experimental notebook, initially record · ~ .title of study .PI,s name .date the study starts (inclusive dates after study ends) .associate investigator (e.g., SRA, postdoctoral fellow, resident)
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, correlated specifically with the methodology notebook Perform study, recording ...specific notes regarding special procedures or steps that differ from specific techniques (including statistical) taken from the methodology notebook, record of any variance from usual BTRC procedures in specific correlation with the methodology notebook ...raw data, including handwritten notes on data collection, endpoints, daily observations, location of photomicrographs and negatives, and particularly notations about excluded data or animals, with detailed information on why they were excluded ...a "time line" illustrating the sequence of study events (e.g., start, cells added, medium added, .
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From page 222... ...
published by the Office of the Senior Vice Chancellor, Academic Affairs, and available in the UCSF Dean's Office and the UCSF Library.
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