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1 Introduction
Pages 1-8

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From page 1...
... government deliberative process. Approximately 125 people attended the event in person, while more than 200 others watched the webcast.2 The first symposium, held in December 2014, examined the underlying scientific and technical questions surrounding the potential risks and 1  As    described in the Draft Working Paper of the National Science Advisory Board for Biosecurity, "the phrase ‘gain-of-function research' has become synonymous with certain studies that enhance the ability of pathogens to cause disease.
From page 2...
... decisions. The public symposium did not attempt to develop consensus recommendations, but rather sought individual perspectives and robust discussion to inform the development of the NSABB's final recommendations.
From page 3...
... Invited attendees should have a diverse range of perspectives and expertise, including but not limited to public health, biosafety, public health surveillance, research, risk assessment experts, public policy makers, security, and drug and vaccine development; the agenda should also include experts from regions of the world where pathogens with pandemic potential are endemic and from regions of the world conducting GOF research on such pathogens. This 2-day symposium will be webcast and the presentations and background materials will be archived online.
From page 4...
... She identified a need to develop a strategic approach to support scientific progress while addressing the impacts for our societies. Jo Handelsman from the White House Office of Science and Technology Policy believed this to be a landmark meeting, one that could direct future policy in important ways.
From page 5...
... Following this, an interagency process led by the Office of Science and Technology Policy will produce a policy that will provide federal oversight for GOF research and replace the funding pause. Carrie Wolinetz from the National Institutes of Health began her remarks by stating that a robust life sciences research endeavor is critical to promoting public health and well-being in light of evolving threats posed by microbial pathogens.
From page 6...
... FIGURE 1-1  Timeline of major events in the gain-of-function deliberative process. NOTE: GOF = gain of function; NSABB = National Science Advisory Board for Biosecurity; USG = U.S.
From page 7...
... , the risk and benefit assessment conducted by Gryphon Scientific (Gryphon Scientific, 2015) , and the ethics report commissioned from Michael Selgelid (Selgelid, 2015)


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