Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets Proceedings of a Symposium (2018) / Chapter Skim
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6 Prospects for Molybdenum-99 Future Supply
6 Prospects for Molybdenum-99 Future Supply
Pages 29-42
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From page 29... ...
For example, • Irradiation facilities that currently irradiate HEU targets for Mo-99 production for medical use (i.e., BR-2, HFR, LVR-15, Maria) may only irradiate LEU targets.
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From page 30... ...
• SAFARI-I2 in South Africa could stop producing Mo-99 when its current operating license expires in 2030. • Several new projects could be completed and producers in Argentina, Brazil, China, Egypt, India, Japan, and South Korea could start producing Mo-99 for domestic and regional supplies.
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From page 31... ...
The question marks on the left of the country flags indicate the uncertainties associated with the production plans and schedules. Representatives from Algeria, Brazil, Japan, Indonesia, and the United States' Niowave and Eden Radio isotopes were unable to participate; an invited potential producer from Poland responded that the Mo-99 production project has been halted; a representative from Nordion, Canada, was unable to provide an update on the collaborative project with General Atomics and the University of Missouri Research Reactor Center.
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From page 32... ...
She added that the proposed process produces highspecific-activity Mo-99, compatible with existing technetium generators, without the need for a nuclear reactor. SHINE's facility in Janesville, Wisconsin, will be an integrated facility for medical isotope production, processing, and target (uranyl sulfate solution)
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From page 33... ...
Northwest Medical Isotopes Northwest Medical Isotopes (NWMI) plans to produce Mo-99 by irradiating LEU targets in a network of existing university research reactors.
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From page 34... ...
Rosatom is planning to test production at the RBMK reactor at Smolensk Nuclear Power Plant, the youngest of the three RBMK reactors5 currently operating in Russia. Karpov Institute is working on designing LEU targets for irradiation at Smolensk and on optimizing the target chemical processing.
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From page 35... ...
When asked by several symposium participants to provide further clarity on the schedule for deciding which project Rosatom will pursue further, he said that he anticipates JSC Isotope will make a decision in 2018 on which method of production from non-HEU sources appears to be the most promising from technological, economic, and market perspectives, and focus on the market readiness of that production method. A fourth prospect for Mo-99 production in Russia is under development at Tomsk Polytechnic University and was presented by Prof.
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From page 36... ...
Some project-specific information is provided in the following sections. TRIUMF TRIUMF collaborates with four other institutions (University of British Columbia, British Columbia Cancer Agency, Centre for Probe Development and Commercialization, and Lawson Health Research Institute)
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From page 37... ...
Dr. Du discussed two current projects in China aiming to produce Mo-99 to cover domestic needs: • China Advanced Research Reactor (CARR)
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From page 38... ...
noted that BARC is currently working with the Argentinian company INVAP to develop capability to produce about 300 six-day Ci/week of high-specific-activity Mo-99 by irradiating LEU targets at the new Apsara reactor or Dhruva reactor. Mo-99 produced at the Apsara or Dhruva reactors will cover domestic needs (estimated at about 200 sixday Ci/week)
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From page 39... ...
He added that receiving regulatory approvals to construct, operate, and sell medical isotopes can also be long processes. Therefore, many of the projects presented at the symposium are unlikely to be market ready by the dates presented at the symposium (and summarized in Table 6.1)
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From page 40... ...
WWR-c 350 Producing currently 700 by 2020 Argentina Fission of U-235 (LEU) RA-3 400 Producing currently N/A Tomsk Polytechnic Neutron capture IRT-T 6 ~10 Resuming production N/A University in 2018 Khlopin Radium Neutron capture RBMK, Leningrad Nuclear ~10 Producing currently N/A Institute Power Plant Egypt Fission of U-235 (LEU)
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From page 41... ...
PALLAS ≥6,200 2025 South Korea Fission of U-235 (LEU) KJRR 500 2022 2,000 by 2025 NOTES: New projects aiming to produce Mo-99 that were not presented at the symposium are not summarized on this table.
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