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Public Health Consequences of E-Cigarettes (2018) / Chapter Skim
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6 Research Needs: E-Cigarette Devices, Constituents, and Exposures
Pages 217-220

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From page 217...
... The committee understands that, in any new field, researchers struggle to conduct optimal research due to limitations of knowledge. Also, researchers feel the urgency to study a new important question and adapt what they know, without complete adjustments in research design or methods sufficient to address the nuances of the problem.
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From page 218...
... Specific items for consideration identified by the committee are noted for each of these and are not listed in any priority order. ADDRESSING GAPS IN SUBSTANTIVE KNOWLEDGE Recommendation 6-1: The committee recommends that the Food and Drug Administration and other federal research spon sors and/or device manufacturers prioritize e-cigarette research that addresses key gaps regarding knowledge about e-cigarette devices, constituents, and exposures.
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From page 219...
... • Develop and validate methods to produce aerosols and to ana lyze target constituents in e-cigarettes; the standardized method should reflect not only the average puffing conditions observed among the users in real-life settings, but also intensive puffing behaviors. • Develop and validate a standardized method to measure par ticle size distribution and respiratory deposition of e-cigarette aerosols.
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Key Terms

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  • addressing gaps
  • specific items

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  • ticle size
  • chemical substance
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  • gaps regarding
  • standardized puffing
  • vor ingredients
  • studies difficult
  • committee understands

  • potentially biologically
  • knowledge recommendation
  • researchers feel
  • biologically relevant
  • substance release

  • vape shops
  • product standards
  • consideration identified
  • statutory deadlines
  • research requires

  • target constituents
  • evaluate changes
  • analytical methods
  • changing nature
  • methods sufficient


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