Skip to main content

Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public-Private Partnerships Proceedings of a Workshop (2018) / Chapter Skim
Currently Skimming:

2 Exploring Challenges to Developing Treatments for Pain and Opioid Use Disorders
Pages 11-16

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 11...
... Moreover, she said, although a survey by Research! America Analytics found that about twothirds of respondents said they know someone who experiences "pain so severe that they sought prescription medications to treat it," only 18 percent described pain as a major public health problem (Research!
Read the entire page →
From page 12...
... Even those who have an opioid use disorder deserve the best, most humane, and empathic medical care, she said. INSUFFICIENT RESOURCES TO TREAT PAIN From a clinical perspective, Veasley noted a shortage of pain specialists; insufficient training on pain for primary care providers; a lack of team-based, multimodal, coordinated treatment; and a meager evidence base on which to assess benefits and risks of any treatment approach.
Read the entire page →
From page 13...
... UNDERSTANDING CHALLENGES IN CONDUCTING CLINICAL TRIALS Elevated placebo responses in pain trials have made it difficult to demonstrate efficacy in clinical trials, said Tor Wager, director of the Cognitive and Affective Neuroscience Laboratory at the University of Colorado Boulder. He commented that the biological, genetic, and
Read the entire page →
From page 14...
... Furthermore, Jessica Hulsey Nickel noted that because there is inadequate reimbursement for drugs that treat addiction or reverse overdose, pharmaceutical companies lack incentives to develop these treatments. THE PENDULUM SWING OF CARE: UNDERSTANDING PATIENT NEEDS Veasley said there has been a pendulum swing in the medical scientific world when it comes to managing pain (see Figure 2-1)
Read the entire page →
From page 15...
... Potential opportunities presented by individual workshop participants to address these challenges are highlighted in succeeding chapters. FIGURE 2-1 Pendulum swing in the medical scientific world: Pain treatment, research, drug development, and the involvement of patients in decision making has swung dramatically in recent years.
Read the entire page →

Key Terms

  • clinical trials
  • pain mechanisms
  • pendulum swing
  • treat pain
  • conducting clinical

  • insufficient understanding
  • placebo responses
  • medical scientific
  • circadian variability
  • opioid user

  • clinical pain
  • efficient clinical
  • pain trials
  • pain disorder
  • described pain

  • surrounding pain
  • pain transition
  • veasley noted
  • pain therapies
  • pain therapy

  • christin veasley
  • managing pain
  • diagnosed chronic
  • pain research
  • pain compared

  • pain treatment
  • federal pain
  • clinical perspective
  • pain responses
  • defines pain


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.