Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research Proceedings of a Workshop (2019) / Chapter Skim
Currently Skimming:
Appendix A: Workshop Agenda
Appendix A: Workshop Agenda
Pages 87-94
The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.
From page 87... ...
Marmosets present certain advantages compared to more traditional nonhuman primate species and may be particularly useful for the development of new disease models using genetic engineering (achieved using the CRISPR/Cas9 technology) and assisted reproductive technologies.
|
From page 88... ...
AGENDA MONDAY, October 22, 2018, Keck 100 8:00AM Welcome and Introduction to Workshop Workshop Co-Chairs: SAVERIO CAPUANO, Wisconsin National Primate Research Center JAMES FOX, Massachusetts Institute of Technology Roundtable Director LIDA ANESTIDOU, Institute for Laboratory Animal Research 8:10AM Keynote: The Historical Use SUZETTE TARDIF, of Callitrichids in Biomedical Southwest National Research and Current Trends Primate Research Center Introduction JAMES FOX
|
From page 89... ...
APPENDIX A 89 Session 1 -- Marmoset Availability 8:40AM Current State of Affairs: Session Moderator: Analyzing the Numbers SAVERIO CAPUANO Objectives: • Inform on the status of marmoset population in the United States • Present one country's approach to meeting its marmoset-dependent research needs • Present a perspective on the conflict between conservation, bioprospecting, and biomedical research • In the context of anticipated demand for marmosets, discuss an equitable, sustainable, and fair control of and access to marmoset resources (numbers, tissues, and genetic material; how supply lines are established and the role of wild caught marmosets) globally Speakers: JON LEVINE, Wisconsin National Primate Research Center ERIKA SASAKI, Central Institute for Experimental Animals, Japan MARIA ADÉLIA BORSTELMANN DE OLIVEIRA, Federal Rural University of Pernambuco, Brazil SAVERIO CAPUANO Q&A with the audience 10:10AM COFFEE BREAK 10:30AM Genetic Diversity in Times Session Moderator: of Increased Demand JAMES PICKEL, National Institute of Mental Health Objectives: • Examine the prospect and application of a Species Survival Plan for marmosets, including its role in the exchange of genetic information (+ small colonies)
|
From page 90... ...
• It appears likely that the U.S. marmoset research population will include a number of breeding colonies that are each relatively small, raising questions as to how to best maintain the overall population to ensure genetic viability.
|
From page 91... ...
There is a cafeteria on the 3rd floor of this building.) Session 2 -- Marmosets as Research Models 1:30PM Using Marmosets in Session Moderator: Biomedical Research MARINA EMBORG, Wisconsin National Primate Research Center Objectives: In order to showcase the versatility of marmosets as animal models, panelists will use examples of different research questions to discuss • Aging research with marmosets • Marmoset-based infectious disease research under biocontainment conditions • The development of marmoset-based neuroscience models • Genomic editing in marmosets • Using behavioral tests (functional magnetic resonance imaging)
|
From page 92... ...
92 CARE, USE, AND WELFARE OF MARMOSETS 3:30PM COFFEE BREAK 3:45PM Ethical Considerations Session Overview: Regarding the Use of ERIC HUTCHINSON, Marmosets in Research Johns Hopkins University Objectives: • Discuss the ethics of genetically modifying the marmoset, a nonhuman primate • Analyze the ethical imperative of being cognizant of your knowledge before starting research with marmosets (small colonies; transport; stress) Speakers: ADAM SHRIVER, Oxford University, United Kingdom STEVEN NIEMI, Harvard University 4:45PM Facilitated Discussion with Session Leader: the Audience ERIC HUTCHINSON 5:30PM End of Day 1 TUESDAY, October 23, 2018, Keck 100 8:15AM Opening of Day 2 and SAVERIO CAPUANO Recap of Day 1 8:30AM Highlights of the workshop MARINA EMBORG on Transgenic and Chimeric Neuroscience Research: Exploring the Scientific Opportunities Afforded by New Nonhuman Primate Models Session 3 -- Marmoset Husbandry 8:45AM Select Topics in Marmoset Session Moderator: Husbandry JACO BAKKER, Biomedical Primate Research Centre, The Netherlands
|
From page 93... ...
• What are the areas of management that are most likely to vary and have the potential to affect animal welfare? • What are the areas of management that are most likely to vary and have the potential to affect study outcomes?
|
From page 94... ...
Session 4 -- Marmoset Veterinary/Clinical Care 1:00PM Select Topics in Marmoset Session Moderator: Veterinary Care ERIC HUTCHINSON Objectives: • Provide a framework for an overall health management of marmoset colonies • Discuss common clinical presentations in and treatments for marmosets • Provide an overview of basic elements of anesthesia and analgesia for marmosets • Present basic facts and practical aspects of marmoset reproduction • Discuss key features of marmoset pathology Speakers: CASEY FITZ, Wisconsin National Primate Research Center JESSICA IZZI, Johns Hopkins University ANNA GOODROE, University of Houston MONIKA BURNS, Massachusetts Institute of Technology KEITH MANSFIELD, Novartis 2:40PM Facilitated Discussion with Session Leader: the Audience ERIC HUTCHINSON Session 5 -- Improving Research Practices That Depend on the Use of Marmosets: Key Messages and Future Actions 4:00PM Closing Session -- Improving Session Leaders: Research Practices That SAVERIO CAPUANO Depend on the Use of JAMES FOX Marmosets: Key Messages and Future Actions 4:30–4:45PM Workshop Adjourns
|
Key Terms
This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More
information on Chapter Skim is available.