The National Academies Press

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1 Introduction
Pages 1-6

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From page 1... ... . One century later, outbreaks and pandemics of influenza and other infectious diseases have caused widespread human suffering and deaths, and continue to pose major threats to public health, health security, and societal and economic stability at the local, national, and global levels. Read the entire page →
From page 2... ... Collective action at local, national, and global levels could strengthen preparedness for infectious disease outbreaks and pandemics by leveraging and intensifying the scientific and political momentum that has gathered over recent decades. WORKSHOP OBJECTIVES In November 2018, an ad hoc planning committee under the auspices of the Forum on Microbial Threats at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics.1 The first was a public, half-day 1 The planning committee's role was limited to planning the workshop, and the Proceedings of a Workshop was prepared by the workshop rapporteurs as a factual summary of what occurred at the workshop. Read the entire page →
From page 3... ... Additionally, panelists, forum members, and attendees were given the opportunity to assemble into small groups and asked to consider potential priority actions and strategies for systematizing and integrating outbreak and pandemic preparedness so that it is a routine activity from the local to global levels. Specifically, participants discussed the following topics during the 1.5day workshop2: • Recent progress achieved in monitoring global health security and pandemic preparedness at national and global levels, including advances in developing national action plans that stem from the Joint External Evaluation, building strong public health capacities that incorporate a One Health approach, and developing risk analysis and assessment tools to guide resource allocation; • Critical challenges and opportunities in developing and evaluating medical countermeasures, including seasonal vaccines, a universal influenza vaccine, and novel diagnostics and therapeutics, as well as strategies to secure their adequate supply and distribution; 2 The full Statement of Task is available in Appendix B Read the entire page →
From page 4... ... Chapter 2 includes highlights from the pre-workshop welcome remarks and the keynote presentation, in which the speaker provided a historical overview of the 1918 influenza pandemic and considered whether the world is ready to respond to the next influenza pandemic. Chapter 3 provides an overview of the pre-workshop panel discussion, in which participants addressed progress in global efforts to prepare for the next influenza pandemic across the realms of virus biology, universal influenza vaccine development, global governance structures, and the One Health approach. Read the entire page →
From page 5... ... Chapter 6 offers private-sector and institutional perspectives on lessons learned in vaccine preparedness and examines the spectrum of challenges in vaccine development, manufacturing, and deployment during the 2009 H1N1 pandemic. Chapter 7 explores global perspectives on and lessons learned about equity and fairness related to preparedness, with a focus on the discussions of virus and benefit sharing that arose out of the 2006 H5N1 outbreak and led to the development of the Pandemic Influenza Preparedness Framework. Read the entire page →

From page 1...

... . One century later, outbreaks and pandemics of influenza and other infectious diseases have caused widespread human suffering and deaths, and continue to pose major threats to public health, health security, and societal and economic stability at the local, national, and global levels.

Read the entire page →

From page 2...

... Collective action at local, national, and global levels could strengthen preparedness for infectious disease outbreaks and pandemics by leveraging and intensifying the scientific and political momentum that has gathered over recent decades. WORKSHOP OBJECTIVES In November 2018, an ad hoc planning committee under the auspices of the Forum on Microbial Threats at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics.1 The first was a public, half-day 1 The planning committee's role was limited to planning the workshop, and the Proceedings of a Workshop was prepared by the workshop rapporteurs as a factual summary of what occurred at the workshop.

Read the entire page →

From page 3...

... Additionally, panelists, forum members, and attendees were given the opportunity to assemble into small groups and asked to consider potential priority actions and strategies for systematizing and integrating outbreak and pandemic preparedness so that it is a routine activity from the local to global levels. Specifically, participants discussed the following topics during the 1.5day workshop2: • Recent progress achieved in monitoring global health security and pandemic preparedness at national and global levels, including advances in developing national action plans that stem from the Joint External Evaluation, building strong public health capacities that incorporate a One Health approach, and developing risk analysis and assessment tools to guide resource allocation; • Critical challenges and opportunities in developing and evaluating medical countermeasures, including seasonal vaccines, a universal influenza vaccine, and novel diagnostics and therapeutics, as well as strategies to secure their adequate supply and distribution; 2 The full Statement of Task is available in Appendix B

Read the entire page →

From page 4...

... Chapter 2 includes highlights from the pre-workshop welcome remarks and the keynote presentation, in which the speaker provided a historical overview of the 1918 influenza pandemic and considered whether the world is ready to respond to the next influenza pandemic. Chapter 3 provides an overview of the pre-workshop panel discussion, in which participants addressed progress in global efforts to prepare for the next influenza pandemic across the realms of virus biology, universal influenza vaccine development, global governance structures, and the One Health approach.

Read the entire page →

From page 5...

... Chapter 6 offers private-sector and institutional perspectives on lessons learned in vaccine preparedness and examines the spectrum of challenges in vaccine development, manufacturing, and deployment during the 2009 H1N1 pandemic. Chapter 7 explores global perspectives on and lessons learned about equity and fairness related to preparedness, with a focus on the discussions of virus and benefit sharing that arose out of the 2006 H5N1 outbreak and led to the development of the Pandemic Influenza Preparedness Framework.

Read the entire page →

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1 Introduction Pages 1-6

1 Introduction
Pages 1-6