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Virtual Clinical Trials Challenges and Opportunities: Proceedings of a Workshop (2019) / Chapter Skim
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Appendix D: Virtual Clinical Trials Presented by Speakers at the Workshop
Pages 105-108

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From page 105...
... This study has the potential to simplify long-term follow-up of large cohorts and will test the feasibility of new technology platforms to fulfill this purpose. For more information, please view the study record (ClinicalTrials.gov, 2019c)
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From page 106...
... • Year Posted: 2019 • Sponsor: National Institute on Aging • Disease: Osteoporosis and Parkinson's disease • Intervention: Zoledronic acid • Phase: Phase 4 • Digital Health Technology: Web- and video-based This study evaluated the efficacy of Zoledronic acid in reducing bone fracture risk in elderly Parkinson's disease patients. The participants enroll through interactive electronic consent, and if deemed eligible to join the study will be scheduled for a video-based telemedicine assessment to confirm ­ arkinson's disease diagnosis.
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From page 107...
... • Intervention: Lithium carbonate • Phase: N/A • Digital Health Technology: Web-based PatientsLikeMe tested the efficacy of lithium carbonate by capturing information on the study's participants via an online data collection tool. Though this study did not show a treatment effect, it did note advantages of collecting patient-reported outcome data online, including speed, patient access, and availability of control participants (Wicks et al., 2011)
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From page 108...
... . Though the study did not find evidence to support use of Lunasin to slow or reverse progression of ALS, the design of the trial did provide logistical benefits, such as cost efficiency, increased diversity of participants enrolled, and rapid enrollment (Bedlack et al., 2019)
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Key Terms

  • lateral sclerosis
  • amyotrophic lateral
  • spectrum disorder
  • lithium carbonate
  • autism spectrum

  • study evaluated
  • carbonate treatment
  • participants enrolled
  • duke als
  • data online

  • bone fracture
  • zoledronic acid
  • including speed
  • provide logistical
  • fracture risk

  • reducing bone
  • interactive electronic
  • cost efficiency
  • virtual study
  • als clinic

  • treatment effect
  • study management
  • note advantages
  • fatty acids
  • disease patients

  • patientslikeme tested
  • deemed eligible
  • logistical benefits
  • rapid enrollment
  • electronic consent


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