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5 Applying the Framework to a New State 2 Data Resource
Pages 78-96

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From page 78...
... This template, based on the cost drivers in each state outlined in Table 4.2, assists in developing a narrative regarding the data life cycle. The approach to forecasting costs for the use cases follows the basic steps described in Table 4.1.
From page 79...
... To establish the necessary neuro­nformatics i infrastructure for data generated through funding, the BRAIN Initiative issued RFAs to (1) ­ evelop the d necessary standards to support the data types generated by BRAIN investigators; (2)
From page 80...
... $386,974c Data Archive Human neurophysiology University of New $1,245,149 for the BRAIN California, $806,242 Initiative San Diego $438,907d OpenNeuro Neuroimaging Stanford 5 TBe $908,521 University $578,676 $329,845 Block and Electron microscopy and Johns Hopkins New $593,507 Object Storage x-ray microtomography University $438,034 Service $155,473f Distributed Neurophysiology Massachusetts New $1,349,674 Archives for Institute of $1,131,040 Neurophysiology Technology $218,634 Data Integration Brain Cell Data Integrated data set for Allen Brain New $2,965,990 Center Brain Cell Census based Institute $2,233,081 on multiple data types $732,909g a 120 TB related to BRAIN project; 1.1 petabytes (PB) total as of July 2, 2019.
From page 81...
... 2 A data archive will develop a data submission pipeline ensuring appropriate quality II.B.1, II.B.7, control standards for laboratories that are trying to upload data. For example, if an II.E.2 experimental standard defines an allowable range of values for a particular data element, the submission pipeline should make sure that uploaded data respect the current data standard.
From page 82...
... The cost forecaster can use this information to consult Table 4.2 to identify likely cost drivers for each activity. that the proposed data resource will be an active repository and platform and therefore a State 2 resource.
From page 83...
... , maintain a help desk (research objective 5) , and make data available to the broad research community, including citizen scientists as appropriate (research objective 6)
From page 84...
... Step 5. Identify the major cost drivers associated with each activity based on the steps above, including how decisions might affect future data use and its cost.
From page 85...
... These functions may need to be multiplied by the number of data types and modalities to be supported, depending on how well the tool set generalizes. Once the resource is mature and data access and use patterns emerge, some significant cost savings may be realized by moving unused or obsolete data to cold storage.
From page 86...
...  Multiple types of imaging data (multimodal data -- light and electron microscopy, multiple microscopy types within each; correlated physiology and genomics.
From page 87...
... W H  Given the size of the data, it would be ideal to have annotation capability > user annotation available to the user base. functions = higher 2.
From page 88...
... The repository is also required to provide means to search other BRAIN repositories through the BRAIN Initiative Data Network. > search 2.
From page 89...
... increased cost 2.  t what level are they instituted (e.g., individual users, individual data A sets)
From page 90...
... > distinctiveness Yes, the Cell Image Library. The EU also has a Bioimaging Database.a = increased cost E. Data Life Cycle E.1 Anticipated 1.
From page 91...
...  re all data originating from the same source (e.g., a single instrument or A increased cost a single organization)
From page 92...
... It is assumed that BRAIN awardees will know of > outreach = our existence. increased costs 2.
From page 93...
...  ill the resource be built using commercial clouds? W to increased costs  Yes, commercial clouds for storage and computation will be used.
From page 94...
...  f data are contributed from multiple sources, will there be a need to I L process multiple kinds of release forms? > ownership =  No, all data will be released under the same license and it will be an open increased costs license per the requirements of the BRAIN Initiative for public data.
From page 95...
... L Reporting No specific information has been requested in the RFA; monthly reports Requirements on acquisitions, total size, and amount of use will be generated for internal purposes. > system-reporting requirements = increased costs I.5 Billing and Will there be charges for use of the resource?
From page 96...
... increased costs  Subject to BRAIN Initiative polices; otherwise, policy set by the resource. J.4 External 1.


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