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Heritable Human Genome Editing (2020) / Chapter Skim
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Appendix D: Acronyms and Abbreviations
Pages 215-218

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From page 215...
... D Acronyms and Abbreviations AG-haESCs Androgenetic haploid embryonic stem cells AIDS Acquired immune deficiency syndrome ARRIGE Association for Responsible Research and Innovation in Genome Editing ART Assisted reproductive technology CAR-T cells Chimeric antigen receptor T cells Cas CRISPR associated protein Cas9 CRISPR associated protein 9 CF Cystic Fibrosis CRISPR Clustered regularly-interspaced short palindromic repeats DNA Deoxyribonucleic acid ES cell Embryonic stem cell ESHRE European Society of Human Reproduction and Embryology FDA Food and Drug Administration FH Familial Hypercholesterolemia gRNA Guide ribonucleic acid HDR Homology-directed repair HFEA Human Fertilisation and Embryology Authority 215
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From page 216...
... 216 HERITABLE HUMAN GENOME EDITING HHGE Heritable human genome editing HIV Human immunodeficiency syndrome hPGCLC Human primordial germ-like cell HSC Hematopoietic stem cell ICH International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use ICM Inner cell mass ICSI Intracytoplasmic sperm injection IFFS International Federation of Fertility Societies IOB International Oversight Board iPSC Induced pluripotent stem cell ISAP International Scientific Advisory Panel IVF In vitro fertilization IVG In vitro gametogenesis LDL Low-density lipoprotein MII Metaphase II MRT Mitochondrial replacement techniques MST Maternal spindle transfer mtDNA Mitochondrial DNA NGS Next-generation sequencing NHEJ Non-homologous end joining ntESC Nuclear transfer embryonic stem cell OHSS Ovarian hyperstimulation syndrome PAM Protospacer-adjacent motif PB Polar body PCR Polymerase chain reaction PGC Primordial germ cell PGCLC Primordial germ cell-like cell PGT Preimplantation genetic testing PNT Pronuclear transfer RNA Ribonucleic acid SART Society for Assisted Reproductive Technology SCD Sickle cell disease SNP Single nucleotide polymorphism
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From page 217...
... APPENDIX D 217 SNV Single nucleotide variant SSC Spermatogonial stem cell TALEN Transcription activator–like effector nuclease WGS Whole-genome sequencing WHO World Health Organization ZFN Zinc-finger nuclease
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