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4 Life Sciences Division
Pages 31-40

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From page 31...
... The results of fundamental research supported by this division are expected to enable the creation of new technologies for optimizing warfighters' physical and cognitive performance capabilities, for protecting warfighters, and for creating new Army capabilities in the areas of biomaterials, energy, logistics, and intelligence.1 The division's core budget of $9.2 million was leveraged against a $67.9 million investment by the Defense Advanced Research Projects Agency (DARPA) and other Department of Defense (DoD)
From page 32...
... Ellington/Glotzer are applying understanding of shape, packing, and assembly of patchy nanoparticles to develop generalizable design principles for protein assembly via charge complementarity. Ellis/Lee are investigating interface synthetic biology and materials science to manipulate the microstructure of bacterial cellulose for reinforcement of lightweight transparent polymeric armor materials.
From page 33...
... Plant species grow in different niches and bloom at different times, surface samples typically contain pollen from multiple species, and species identification can reveal where the item came from, sometime narrowing the source down to tens of square miles but at other times pointing to a single building. Current state of the art is microscopic analysis, done by an expert forensic palynologist, which requires 2 weeks (and expert forensic palynologists are in short supply)
From page 34...
... There is a substantial program of projects on mitochondrial genomic integrity and regulation with the eventual goal of extending warfighters' health, performance, and longevity in active service. The mitochondrial health project presented is a high-risk/high-payoff project that grew out of an initial observation that zebra fish and rodents can be put into a state of suspended animation, with no heartbeat or brain activity, by exposure to hydrogen sulfide, and that these organisms can be brought back to life after several hours of exposure and suffer no detectable adverse effects.
From page 35...
... MICROBIOLOGY PROGRAM Overall Scientific Quality and Degree of Innovation The goal of the Microbiology Program is to identify and understand the fundamental principles governing microbial communities and their eukaryotic interactions, with the eventual goal of exploiting microbiome capabilities for biomanufacturing and for enhanced warfighter performance and protection. The program focuses on three general topics -- two associated with analysis and understanding of bacterial communities and one focused on metabolic programming under environmental stress.
From page 36...
... The projects focused on development of robust means of biomanufacturing are primarily among the SBIR and STTR projects, and the level of innovation is not clear. Nonetheless, some projects are addressing basic needs for analyzing complex communities.
From page 37...
... The specific MURI projects highlighted were (1) developing closed-loop adaptive algorithms and models of multisensory neural activity to maximize brain-computer interface information transfer rate and enhance decision accuracy; and (2)
From page 38...
... SOCIAL AND BEHAVIORAL SCIENCES PROGRAM Overall Scientific Quality and Degree of Innovation The vision of the Social and Behavioral Sciences Program is to identify and characterize micro-tomacro links tying human characteristics to population dynamics embedded within natural and physical systems to improve detection of emerging social dynamics and security risks in multidomain operations. The program has three strategic objectives: (1)
From page 39...
... Relevance and Transitions The potential long-term applications of the Social and Behavioral Sciences Program's projects are readily apparent, with the ability to predict social unrest and to understand influence networks being particularly important. Current transitions consists of briefings of results and predictive models of human errors, human behavior, and sociopolitical dynamics delivered to and used by the U.S.
From page 40...
... to work together on a single SI grant. This mechanism for crossing disciplinary boundaries to accomplish innovative studies has produced outstanding results.


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