Harmonizing the Process for Establishing Nutrient Reference Values A Tool Kit (2020) / Chapter Skim
Currently Skimming:
Part 2: A Conceptual Foundation for Developing Nutrient Reference Values
Part 2: A Conceptual Foundation for Developing Nutrient Reference Values
Pages 7-12
The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.
From page 7... ...
While this tool kit cannot resolve these challenges, it can provide guidance to countries and regions for utilizing existing tools and resources in a way that facilitates consistency in the approach to deriving NRVs. Guiding Principles for Setting Reference Values As described in the Global Harmonization Proceedings of a Workshop and reiterated in the consensus study report, the two core reference values are the average requirement (AR)
|
From page 8... ...
Traditionally, chronic disease has not been a priority outcome, although it is a growing concern among low- and middle-income countries. Current Process for Deriving Nutrient Reference Values Currently, the process to establish NRVs is initiated by an authoritative body, such as a sponsoring government agency or scientific body.
|
From page 9... ...
A systematic evidence-based review will serve as the basis for deliberation, which includes assessing nutrient requirements for age/gender groups; and establishing findings and conclusions about the nutrient under review. A de novo literature review will include information about the search criteria, inclusion and exclusion criteria, study quality criteria, data summaries, and correspondence and consistency of the study task with the methodology to be used in the review.
|
From page 10... ...
This means determining how characteristics of the populations of interest, such as body size, lifestyle, environment, or other factors, may influence the recommended nutrient intake level. These four actions are embedded in a series of steps illustrated in the following flow diagram (see Figure 1)
|
From page 11... ...
11 Authoritative body or expert panel identified nutrient for review Accept, revise existing, or Convene expert nutrient review conduct new systematic panel review Evaluate existing NRVs Option to establish new Option to keep and update or adapt NRV NRV Define approach Describe the nutrient and outcomes selected and approach used Dose–response Factorial approach assessment Describe the evidence base Appraise the evidence Evaluate usual intakes and dietary Evaluate usual intakes patterns and dietary patterns Document adjustments to local context Assess local context Accept, revise, or derive NRVs FIGURE 1 Flow diagram for deriving nutrient reference values (NRVs)
|
From page 12... ...
Differences in physiologic state or body composition that exist between different populations must also be considered. To illustrate, when referring to body weight or energy intake a decision must be made about whether to base the requirement on existing body weights and energy intakes of the population or on reference weights regarded as "healthy" for given height and exercise level.
|
Key Terms
This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More
information on Chapter Skim is available.