The National Academies Press

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From page 356... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief Proceedings of a Workshop IN BRIEF April 2021 LEARNING FROM RAPID RESPONSE, INNOVATION, AND ADAPTATION TO THE COVID-19 CRISIS Proceedings of a Workshop -- in Brief The world continues to grapple with the profound and unprecedented impacts of the COVID-19 pandemic, which by January 2021 had infected more than 90 million people worldwide and taken over 1.9 million lives.1 The crisis quickly mobilized action by universities, industry, and federal, state, and local governments to organize resources and networks; instigate new partnerships; adapt to changing and uncertain circumstances; and innovate solutions to mounting public health and economic challenges. The crisis has also catalyzed broader conversations about the pace of science, the agil ity of scientific collaboration and partnership, the importance of international scientific coordination, and the signifi cance of the public value of science. Read the entire page →
From page 357... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief COVID has been an enormous tragedy, there is important learning to take to heart." Using slides prepared by his NIH colleague Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease, Austin first presented a scientific overview of SARS-CoV-2, noting it is one of many coronaviruses that are mostly common and mild. Others were severe but died out before they became global pandemics. Read the entire page →
From page 358... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) , it has been able to prioritize drugs under a master protocol, initiate clinical trials, and ensure alignment across efforts. Read the entire page →
From page 359... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief and Universities (HBCUs) who had offered support from their institutions in the search for a vaccine. Read the entire page →
From page 360... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief According to Mensah, the response to COVID-19 has broader implications for clinical and public health practice and research. He suggested the following areas of impact: 1. Read the entire page →
From page 361... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief to preparedness and mitigation, as well as to response and recovery after a disaster. Abramson noted that an amalgam of public and private entities must be coordinated during a disaster, and ideally the connections and relationships are built beforehand to create an infrastructure for response. Read the entire page →
From page 362... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief Response Research infrastructure.12 Rapid response teams could develop pre-approved Institutional Review Board (IRB) agreements, for example. Read the entire page →
From page 363... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief to the value of an entity like NASEC, which could be led by academic institutions and involve other entities, and could prevent disjointed and inefficient responses to future disasters. As context, Marder commented that natural disasters, including earthquakes, tsunamis, storms, and fires, and human-made disasters, including chemical, biological, and cyber terrorist attacks, require a concerted and intelligent response to mitigate, and perhaps offset, the negative impacts on society. Read the entire page →
From page 364... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief age people to donate.17 The site leverages the Microsoft Azure Health bot to prequalify potential donors and inform them of nearby donation centers.18 No personal data are collected. Working with OWS, they targeted 14 high-interest communities. Read the entire page →
From page 365... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief to partner with these other entities, including Hewlett Packard, NISSHA Medical Technologies, MIT, and Purdue Univer sity on pandemic response-related research and production. At the end of the day, he said, to achieve science, speed, and scale, it is important to have innovation in fundamental science and capabilities; engineering and scale manufacturing expertise and infrastructure; and external collaborations. Read the entire page →
From page 366... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief tion, but schools without the capacity that Massachusetts has are more vulnerable. She called for a way to incent this kind of movement. Read the entire page →
From page 367... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief pansion, and kitting and distribution. In vaccine development, the federal government is assuming the financial burden of setting up parallel activities to expedite development. Read the entire page →
From page 368... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief bility in submitting applications, including deadlines and research guidance related to humans and animals. Peer review has been conducted virtually. Read the entire page →
From page 369... ... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief cine, and social science, in addition to biomedical sciences. Post-pandemic ideas to empower and stimulate change include making research challenge-driven and funding the teams, not just specific ideas, so they can be innovative. Read the entire page →

From page 356...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief Proceedings of a Workshop IN BRIEF April 2021 LEARNING FROM RAPID RESPONSE, INNOVATION, AND ADAPTATION TO THE COVID-19 CRISIS Proceedings of a Workshop -- in Brief The world continues to grapple with the profound and unprecedented impacts of the COVID-19 pandemic, which by January 2021 had infected more than 90 million people worldwide and taken over 1.9 million lives.1 The crisis quickly mobilized action by universities, industry, and federal, state, and local governments to organize resources and networks; instigate new partnerships; adapt to changing and uncertain circumstances; and innovate solutions to mounting public health and economic challenges. The crisis has also catalyzed broader conversations about the pace of science, the agil ity of scientific collaboration and partnership, the importance of international scientific coordination, and the signifi cance of the public value of science.

Read the entire page →

From page 357...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief COVID has been an enormous tragedy, there is important learning to take to heart." Using slides prepared by his NIH colleague Anthony Fauci, Director of the National Institute of Allergy and Infectious Disease, Austin first presented a scientific overview of SARS-CoV-2, noting it is one of many coronaviruses that are mostly common and mild. Others were severe but died out before they became global pandemics.

Read the entire page →

From page 358...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) , it has been able to prioritize drugs under a master protocol, initiate clinical trials, and ensure alignment across efforts.

Read the entire page →

From page 359...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief and Universities (HBCUs) who had offered support from their institutions in the search for a vaccine.

Read the entire page →

From page 360...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief According to Mensah, the response to COVID-19 has broader implications for clinical and public health practice and research. He suggested the following areas of impact: 1.

Read the entire page →

From page 361...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief to preparedness and mitigation, as well as to response and recovery after a disaster. Abramson noted that an amalgam of public and private entities must be coordinated during a disaster, and ideally the connections and relationships are built beforehand to create an infrastructure for response.

Read the entire page →

From page 362...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief Response Research infrastructure.12 Rapid response teams could develop pre-approved Institutional Review Board (IRB) agreements, for example.

Read the entire page →

From page 363...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief to the value of an entity like NASEC, which could be led by academic institutions and involve other entities, and could prevent disjointed and inefficient responses to future disasters. As context, Marder commented that natural disasters, including earthquakes, tsunamis, storms, and fires, and human-made disasters, including chemical, biological, and cyber terrorist attacks, require a concerted and intelligent response to mitigate, and perhaps offset, the negative impacts on society.

Read the entire page →

From page 364...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief age people to donate.17 The site leverages the Microsoft Azure Health bot to prequalify potential donors and inform them of nearby donation centers.18 No personal data are collected. Working with OWS, they targeted 14 high-interest communities.

Read the entire page →

From page 365...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief to partner with these other entities, including Hewlett Packard, NISSHA Medical Technologies, MIT, and Purdue Univer sity on pandemic response-related research and production. At the end of the day, he said, to achieve science, speed, and scale, it is important to have innovation in fundamental science and capabilities; engineering and scale manufacturing expertise and infrastructure; and external collaborations.

Read the entire page →

From page 366...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief tion, but schools without the capacity that Massachusetts has are more vulnerable. She called for a way to incent this kind of movement.

Read the entire page →

From page 367...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief pansion, and kitting and distribution. In vaccine development, the federal government is assuming the financial burden of setting up parallel activities to expedite development.

Read the entire page →

From page 368...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief bility in submitting applications, including deadlines and research guidance related to humans and animals. Peer review has been conducted virtually.

Read the entire page →

From page 369...

... Learning from Rapid Response, Innovation, and Adaptation to the COVID-19 Crisis: Proceedings of a Workshop–in Brief cine, and social science, in addition to biomedical sciences. Post-pandemic ideas to empower and stimulate change include making research challenge-driven and funding the teams, not just specific ideas, so they can be innovative.

Read the entire page →

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