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7 Revising ATSDR's PFAS Clinical Guidance
Pages 154-159

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From page 154...
... should update its PFAS clinical guidance to make it more succinct and accord with the review of PFAS-associated health effects, exposure reduction considerations, PFAS testing recommendations and interpretation, and recommendations for clinical follow-up presented in this report. When describing the health effects of PFAS, ATSDR should avoid using terms typically used to categorize toxicants, such as "endocrine disrupter" or "neurotoxin," because they are vague and not necessarily clinically meaningful.
From page 155...
... A review of the evidence on the health effects of PFAS should be completed by an authoritative neutral party every 2 years, and the clinical guidance should be updated every 5 years or sooner if warranted by the evidence on the health effects of PFAS. Clinicians and members of communities with elevated PFAS exposure should be engaged to inform the problem and review updated guidance.
From page 156...
... It will also be important for ATSDR to update its reviews regarding PFAS-associated health effects, as well as to catalyze future research by identifying gaps in the evidence. This process should include both a review of guidelines issued by other authoritative bodies reflecting decisions about the health effects of PFAS and a review of the epidemiologic literature to identify any new studies that may warrant updating or revising ATSDR's own authoritative guidance.
From page 157...
... and the USPSTF recommendations. The process for updating the literature review should encompass studies on PFAS exposure reduction, including those evaluating behavior change, interventions, or clinical measures, as well as studies on risk-based levels of PFAS to inform clinical care.
From page 158...
... CONCLUSION The need for clear clinical guidance regarding PFAS exposure has only increased, despite the remaining uncertainties regarding the specific health risks of exposure. Yet it is difficult to distill the necessary information for effective clinical practice with respect to PFAS exposure, its possible health effects, and options for shared decision making once exposure has been confirmed.
From page 159...
... Medical Monitoring Program screening tests prepared by the medical panel for the C-8 class members. http://www.c-8medicalmonitoring (accessed January 28, 2022)

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