Skip to main content

Scanning for New Evidence on Riboflavin to Support a Dietary Reference Intake Review (2021) / Chapter Skim
Currently Skimming:

4 Discussion and Future Directions
Pages 43-48

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 43...
... This evidence scan was carried out to obtain new information on riboflavin in association with health outcomes, including adequacy, chronic disease risk, and toxicity. An iterative process of evaluation and adjustment was needed in order to obtain the most relevant evidence to inform identifying and selecting relevant studies.
Read the entire page →
From page 44...
... However, the committee also fully recognizes that such countrylevel assessments of applicability risks missing nuances, such as within-country differences and disparities in health, nutritional status, socioeconomic factors, and access to care. The committee realizes that contemporary populations frequently add supplements to their nutrient intake and that the search required articles to be indexed using terms for "diet" and other potentially restrictive concepts.
Read the entire page →
From page 45...
... Most studies conducted outside of the United States and Canada were excluded in the full-text screening, when the committee ascertained that the populations studied in lower-middle- and low-income countries were not comparable with those in both countries. Of the remaining studies, one was deemed relevant only when it described participants who met the inclusion criteria (see Chapter 2, Table 2-1)
Read the entire page →
From page 46...
... In the absence of a validated biomarker or surrogate marker and/or uncertainty about dietary intake estimates, the committee notes a need to identify a means to consider new and emerging intake estimate methodologies. This could include nontraditional methods to obtain estimates of nutrient status, such as -omics technology to detect riboflavin status.
Read the entire page →
From page 47...
... 2017. Guiding principles for developing Dietary Reference Intakes based on chronic disease.
Read the entire page →

Key Terms

  • chronic disease
  • riboflavin status
  • dietary reference
  • analytic framework
  • future evidence

  • committee identified
  • relevant studies
  • potentially relevant
  • disease risk
  • reference intakes

  • inclusion criteria
  • comprehensive systematic
  • clinical outcomes
  • systematic review
  • dri review

  • relevant evidence
  • evidence synthesis
  • committee realized
  • relevant articles
  • dietary intake

  • reporting riboflavin
  • riboflavin intake
  • outcome relationships
  • iterative process
  • data reporting

  • potential toxicities
  • blood pressure
  • prespecified criteria
  • studies identified
  • screening process


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.