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Appendix F: U.S. Preventive Service Task Force Research Needs Statements from I Statements Issued Between 2017 and 2021
Pages 183-200

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From page 183...
... • Studies examining the benefits and harms of screening for and treatment of gestational diabetes in pregnant persons before 24 weeks of gestation. • Studies reporting on the effects of screening for gestational diabetes on populations defined by race/ethnicity, age, and other relevant socioeco nomic factors.
From page 184...
... from amplification. Tobacco Smoking Cessation in Adults, Including Pregnant Persons: Interventions (USPSTF, 2021b)
From page 185...
... • Pharmacotherapy in pregnant persons: Although behavioral counseling interventions have been found to be effective in improving smoking cessation during pregnancy, additional research is needed on pharma cotherapy options, in particular NRT, for pregnant persons for whom behavioral counseling interventions alone are not effective. º Larger studies adequately powered to detect an effect on both smok ing cessation rates (during pregnancy and postpartum)
From page 186...
... High Blood Pressure in Children and Adolescents: Screening (USPSTF, 2020c) November 10, 2020 There are several critical evidence gaps in understanding the potential net benefit of screening for high blood pressure in childhood and adolescence.
From page 187...
... Tobacco Use in Children and Adolescents: Primary Care Interventions (USPSTF, 2020e) April 28, 2020 More studies are needed to identify effective interventions to help children and adolescents who use tobacco products to quit.
From page 188...
... April 7, 2020 More studies are needed to evaluate screening for and treatment of asymptomatic bacterial vaginosis in pregnant persons at increased risk for preterm delivery. These studies should • Include pregnant persons with a history of prior preterm delivery, as well as other risk factors for preterm delivery, such as cervical insufficiency, multifetal gestation, young or advanced maternal age, low maternal body mass index (<20)
From page 189...
... December 10, 2019 Addressing several key research gaps could help inform the benefit of screening for AAA in U.S.-based populations1: • Although evidence shows that women who smoke or have a family his tory are at increased risk for AAA compared with nonsmoking women without a family history, evidence is insufficient that screening this pop ulation confers a net benefit. Ideally, appropriately powered RCTs among women with risk factors could answer these critical gaps in the evidence on screening for AAA.
From page 190...
... Studies reporting intermediate and health outcomes, outcomes in newborns, and harms in women and infants are needed, as well as studies evaluating effective interventions for reducing blood lead levels in pregnant women. Research is also needed to evaluate the effectiveness of treatments for elevated blood lead levels in trials with adequate sample sizes to inform treatment strategies.
From page 191...
... Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: Screening (USPSTF, 2018f) October 23, 2018 There are several key research gaps related to IPV.
From page 192...
... These studies should evaluate the optimal duration, format, and method of delivery. Trials of ongoing support services should enroll women of all ages, including nonpregnant women and women beyond reproductive age.
From page 193...
... Good-quality studies comparing traditional risk assessment with traditional risk assessment plus the ABI, hsCRP level, or CAC scores are needed to measure the effect of adding nontraditional risk factors on clinical decision thresholds and patient outcomes (CVD events and mortality)
From page 194...
... The development of prognostic models incorporating age, baseline BMD, and hormone replacement therapy use27,28 may also help identify optimal screening intervals. Cardiovascular Disease Risk: Screening with Electrocardiography (USPSTF, 2018c)
From page 195...
... Skin Cancer Prevention: Behavioral Counseling (USPSTF, 2018i) March 20, 2018 A better understanding of the effectiveness of counseling on the use of sun protection behaviors in adults 25 years and older is needed to address the key evidence gap on counseling for this age group.
From page 196...
... March 28, 2017 Studies that randomly assign participants to screening versus no screening and evaluate clinical outcomes are lacking. However, screening studies that target populations at increased risk for celiac disease are likely to be more informative than trials that target the general population, because of the higher prevalence of disease, and should be given higher priority.
From page 197...
... However, in reviewing the currently available evidence on the benefits and harms of performing screening pelvic examinations in asymptomatic adult women, the USPSTF identified the following critical evidence gaps. Studies evaluating the accuracy and effectiveness of screening pelvic examination to detect conditions other than ovarian cancer, bacterial vaginosis, genital herpes, and trichomoniasis are lacking.
From page 198...
... 2018d. Cardiovascular disease: Risk assessment with nontraditional risk factors.
From page 199...
... 2021c. Tobacco smoking cessation in adults, including pregnant persons: Interventions.


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