Physics of Life (2022) / Chapter Skim
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Pages 214-214
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The therapeutic potential for this discovery is being explored as evidence gathers that liquid-liquid phase separation or its misregulation may be at the root of protein aggregation diseases such as Alzheimer's disease, Parkinson's disease, or amyotrophic lateral sclerosis. A major thrust in the application of physics to developmental biology centers on how systems of motor proteins and cytoskeletal filaments in cells couple to cell cell and cell-extracellular matrix (ECM)
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