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Appendix D: Epidemiology: Select Diseases
Pages 461-484

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From page 461...
... . Again, however, children were not included, and Sjögren's disease commonly co-occurs with other autoimmune diseases, so while this prevalence may reflect primary Sjögren's disease in adults, it fails to capture the full extent of individuals in the United States with Sjögren's disease.
From page 462...
... SYSTEMIC LUPUS ERYTHEMATOSUS Epidemiology Overview A recent meta-analysis based on data from a Centers for Disease Control and Prevention (CDC) network of four national lupus registries estimated overall SLE incidence in the United States as 5.1 per 100,000 person years for 2002 to 2009 (Izmirly et al., 2021a)
From page 463...
... Investigators have conducted a meta-analysis of data from the California, Georgia, Michigan, and New York studies and from the Indian Health Service and estimated a prevalence of SLE for the United States of 72.8 per 100,000 (Izmirly et al., 2021b)
From page 464...
... al, 2014. B Incidence of Systemic Lupus Erythematosus in Women in Fulton and DelKalb Counties, Georgia, 2002-2004 by age and race.
From page 465...
... In a study of the U.S. Medicaid beneficiary population from 2000 to 2004, the annual incidence of SLE in children 3 to <18 years old was 2.22 per 100,000 Medicaid-enrolled children and that of lupus nephritis, a frequent complication of SLE, was 0.72 per 100,000 (Hiraki et al., 2012)
From page 466...
... 466 ENHANCING NIH RESEARCH ON AUTOIMMUNE DISEASE A B FIGURE D-2  Incidence and prevalence of SLE in women residents of New York County (Manhattan) , showing age and race and ethnicity.
From page 467...
... . A large study of hospitalized children with SLE in the United States, using data from the Kids' Inpatient Database,2 found both regional and racial disparities in mortality, with Black children and children from southern states having twice the risk of death compared with White children and children from northeastern states (Knight et al., 2014)
From page 468...
... . RHEUMATOID ARTHRITIS Epidemiology Overview Rheumatoid arthritis is one of the most common autoimmune diseases, affecting an estimated 2.4 million adults in the United States PREPUBLICATION COPY -- Uncorrected Proofs
From page 469...
... . Although incidence rates for rheumatoid arthritis decreased in the United States and Europe in the latter part of the 20th century, the trends since the 1990s have demonstrated relatively stable or somewhat rising rates (Myasoedova et al., 2010; Safiri et al., 2019)
From page 470...
... . The prevalence of IBD in children under 17 years of age is about 77.0 per 100,000 people in the United States, which PREPUBLICATION COPY -- Uncorrected Proofs
From page 471...
... . Using the presence of tTGA in serum samples to provide an estimate of disease in the United States, a study based on data from the National Health and Nutrition PREPUBLICATION COPY -- Uncorrected Proofs
From page 472...
... . PRIMARY BILIARY CHOLANGITIS Epidemiology Overview The incidence of PBC in the United States is 4 to 5 per 100,000 persons per year (Lu et al., 2018)
From page 473...
... MULTIPLE SCLEROSIS Epidemiology Overview Multiple sclerosis is the most common CNS inflammatory disorder, though incidence data for the United States do not exist. The overall 2010 U.S.
From page 474...
... . An estimated 178,000 individuals under the age of 20 have type 1 diabetes in the United States (Dabelea et al., 2014)
From page 475...
... AUTOIMMUNE THYROID DISEASES Epidemiology Overview Despite being among the most common autoimmune disorders (Bülow Pedersen and Laurberg, 2009) , there is a lack of detailed epidemiologic data on Hashimoto's thyroiditis and Graves' disease for the past 20 years for the United States.
From page 476...
... 2021. Inflammatory bowel diseases among first-generation and second-generation im migrants in Denmark: A population-based cohort study.
From page 477...
... 2021. Psoriasis prevalence in adults in the United States.
From page 478...
... 2018. Prevalence of diagnosed diabetes in adults by diabetes type - United States, 2016.
From page 479...
... 2020. Prevalence of Sjögren's syndrome associated with rheumatoid arthritis in the USA: An observational study from the Corrona registry.
From page 480...
... 2021b. Prevalence of systemic lupus erythematosus in the United States: Estimates from a meta-analysis of the centers for disease control and prevention national lupus registries.
From page 481...
... 2014. National trends in pediatric systemic lupus erythematosus hospitalization in the United States: 2000–2009.
From page 482...
... 2017. Systematic review of rheumatic disease epidemiology in the indigenous populations of Canada, the United States, Australia, and New Zealand.
From page 483...
... 2017. Fluctuations in the incidence of type 1 diabetes in the United States from 2001 to 2015: A longitudinal study.
From page 484...
... 2020. Prevalence of inflammatory bowel dis ease in pediatric and adult populations: Recent estimates from large national databases in the United States, 2007–2016.


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