Enhancing NIH Research on Autoimmune Disease (2022) / Chapter Skim
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Appendix G: Analysis of the NIH Autoimmune Disease Research Grant Portfolio: Methodology
Appendix G: Analysis of the NIH Autoimmune Disease Research Grant Portfolio: Methodology
Pages 501-510
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From page 501... ...
They are described below, along with the methods used to describe different aspects of the research portfolio (spending on autoimmune disease research by NIH and Institute and Centers (ICs) ; spending on autoimmune disease research by research activity; spending on autoimmune disease research by disease; IC collaborations; clinical trials, publications, and patents associated with autoimmune disease research grants; and an analysis of study sections reviewing autoimmune disease grants)
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RePORTER RePORTER is a publically available electronic database that "allows users to search a repository of both intramural and extramural NIHfunded research projects from the past 25 years and access publications since 1980, and patents resulting from NIH funding."4 RePORTER draws from a number of internal and external databases to compile information associated with research projects. These include the electronic research administration (eRA)
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Autoimmune Disease Spending Methodology The committee used the NIH RePORTER database to evaluate funding and other aspects of the NIH autoimmune disease research portfolio. The RePORTER database allows users to query or search by the spending categories specified by RCDC (presented as "NIH Spending Category" in the RePORTER advanced projects search)
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Creation of New Dataset Variables Two new variables were created to support specific committee analyses related to the type of research funded, and to provide a more complete estimate of the total cost of autoimmune disease research funding. These new variables are described below.
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From page 505... ...
Due to the different purposes of the data systems, neither system provides a complete estimate of the total cost of autoimmune disease research funding by IC. The committee created a new variable, Combined Total Cost of Funded Autoimmune Research to address this issue and added it to the CRD.
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Research projects can 9 The M activity code, also known as general clinical research centers program, is an award made to an institution solely for the support of a General Clinical Research Center where scientists conduct studies on a wide range of human diseases using the full spectrum of the biomedical sciences. The P activity code, also known as program/project center grants, are large, multidisciplinary and long-term research efforts that generally include a diverse array of research activities.
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From page 507... ...
This methodology was used in the analyses associated with Table 6-8. Study Section Analysis The committee used the online CSR study section tool available at https://public.csr.nih.gov/StudySections.10 The committee entered the name of each of the select autoimmune diseases of committee interest into the study section search field to identify the names of its associated chartered study sections.
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Publications To determine the publications associated with the autoimmune disease grants of interest, a variety of NIH and public databases were used, including PubMed, Scientific Publication Information Retrieval and Evaluation System (SPIRES) bibliometric tools, and Web of Science (WoS)
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From page 509... ...
and RePORTER. Patent data was linked to 8,470 autoimmune disease grants of interest using a matching.
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