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Using Population Descriptors in Genetics and Genomics Research A New Framework for an Evolving Field (2023) / Chapter Skim
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Pages 177-184

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From page 177...
... APPENDIX A 177 Stacy Christiansen Managing Editor, JAMA Chair, AMA Manual of Styles Hannah Wand Director, Preventive Genomics Program Genetics Counselor Stanford Health Care 4:55–5:00 p.m. Concluding Remarks 5:00 p.m.
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From page 179...
... Ancestral recombination graph: For a set of individuals, the graph depicting the genetic ancestry lines (or paths) that trace back to their common genetic ancestors at every position in the genome (Hudson, 1990)
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From page 180...
... . Ethnicity: a sociopolitically constructed system for classifying human beings according to claims of shared heritage often based on perceived cultural similarities (e.g., language, religion, beliefs)
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From page 181...
... of genetic similarity. See also Ancestral recombination graph, Ancestry, Genealogical ancestors, Genetic ancestors, Genetic ancestry group, and Genetic similarity.
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From page 182...
... . See also Ancestry, Genealogical ancestors, Genetic ancestors, Genetic ancestry, and Genetic ancestry group.
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From page 183...
... Natural selection: the process whereby some individuals, better adapted to their surroundings, are more likely to survive and leave descendants. If a trait under selection is heritable, natural selection can lead to change in trait values over generations through changes in causal allele frequencies (Emlen and Zimmer, 2020)
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From page 184...
... 2023. Genetic similarity versus genetic ancestry groups as sample descriptors in hu man genetics.
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Key Terms

  • genealogical ancestors
  • genetic ancestry
  • human genetic
  • genetic similarity
  • genetic ancestors

  • family tree
  • human genetics
  • american journal
  • population descriptor
  • human populations

  • ancestral recombination
  • environmental exposures
  • recombination graph
  • geographic location
  • genetic variants

  • disease risk
  • shared genetic
  • allele frequencies
  • perceived cultural
  • cultural similarities

  • ranking human
  • entire genome
  • ancestry lines
  • natural selection
  • sociopolitically constructed

  • polygenic risk
  • american sociological
  • examples include
  • recently admixed
  • labels based


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