Biomarkers for Traumatic Brain Injury Proceedings of a Workshop (2023) / Chapter Skim
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1 Introduction
1 Introduction
Pages 1-6
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This heterogeneity makes it challenging to accurately assess injury, effectively deliver care, and optimize outcomes for people and families that experience a TBI. To advance care and research, an ongoing goal for the field has been to identify and validate a tool kit of biomarkers that are able to more precisely and objectively diagnose and categorize a suspected TBI, better guide and monitor treatment and recovery after injury, and refine the design of future research studies.
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; acute care and classification socia l of the nature of the TBI in settings such as emergency departments; provision BIOG LO l of rehabilitation interventions iCa and ongoing follow-up; and longer-term recovery and reintegration back into society. chological ecological psy chological chological psy social psy social social l gicaLOG ecolo BIO psy chological BIO STAGES OF A CARE JOURNEY AFTER TBI BIO social LOG iCal LOG iCal iCal BIO LOG chological psy iCal FOR MANY, THE JOURNEY social IS NOT RECOVERY AND CONTINUOUS OR SMOOTH.
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Hoffman shared key dimensions of biomarkers that will need to be considered when assessing their uses for TBI care and research; these are summarized in Figure 1-2 and include the type of marker, purpose to which the marker can be applied, and the phase of care during which the marker's information is most relevant. ORGANIZATION OF THE WORKSHOP The newly created Forum on Traumatic Brain Injury at the National Academies of Sciences, Engineering, and Medicine hosted a 1-day workshop that explored the use of biomarkers to diagnose and classify a suspected TBI, guide and monitor treatment after injury, and refine future research studies.
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Later sessions explored the state of the science in major classes of biomarkers, the research and development pathways, and opportunities for advancing biomarker use, including emerging initiatives at the national level. Finally, discussions centered on where the TBI community wants to go moving forward and how to realize these goals.
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Chapter 4 highlights several near-term opportunities to advance the implementation of biomarkers in TBI clinical practice, including an updated classification approach. Finally, Chapter 5 identifies thematic areas and key messages discussed by workshop speakers and participants during the meeting, along with remaining challenges and questions to be addressed.
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