Harnessing Innovative Biotechnologies for National Security in Material and Human Dimensions Abridged Version (2023) / Chapter Skim
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Appendix 1: Committee Meetings and Workshops
Appendix 1: Committee Meetings and Workshops
Pages 2-12
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The objectives are to Highlight new research into connections and mediators along the gut–brain axis Recognize challenges or limitations across related fields Identify transdisciplinary technologies and their potential applications Explore the ecosystem that supports or is needed to support future development Envision where the field could be in 10 years All sessions will address the following questions: What are current areas of convergence across gut– brain-axis research, and how can biotechnologies best be integrated to overcome barriers to application? THURSDAY, DECEMBER 15, 2022 OPEN 11:00–11:15 am EST Welcome Kavita Berger and Diane DiEuliis Welcome and Overview Elliot Chaikof, Harvard University 11:15 am–12:30 pm EST Integrating Sensory and Immunological Input The goal of this introductory session is to set the stage for considering the links between gut microbiota and nervous and immune systems, or the gut–brain axis.
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The discussion provides an opportunity for speakers and committee members to discuss trends and interests in studying multisystem human physiology, as well as the technological and scientific needs for continued advancement, limitations of current research, ideas to address health and societal needs, and possible opportunities for further studies and applications. Moderator: Elliot Chaikof, Harvard University END OF FIRST DAY FRIDAY, DECEMBER 16, 2022 OPEN 11:00–11:10 am EST Welcome and Summary of Day 1 Moderator: Elliot Chaikof, Harvard University 3
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Immune Regulation of the Gut-Brain Axis by the Gut Microbiome in Early Life Vanessa Ridaura, Gates Foundation (virtual) Maternal Microbiome Directed Interventions to Improve Pregnancy and Infant Outcomes in LMIC Geographies Michael Fischbach, Stanford University (virtual)
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Moderator: Jun Axup, E11 Bio William Bonvillian, Massachusetts Institute of Technology (virtual) Panelists: Elaine Hsiao, University of California, Los Angeles Mauro Costa-Mattioli, Altos Labs Hubert Lim, University of Minnesota Vanessa Ridaura, Gates Foundation 3:45–4:00 pm EST Closing Remarks Moderator: Elliot Chaikof MEETING ADJOURNS Biotechnology Capabilities for National Security Needs Discussion December 15, 2022 OPEN Meeting Goals This discussion is to provide opportunities for the sponsor and colleagues to ask their specific questions about the scientific content of the associated workshop, and to provide the committee members to understand possible real-world relevance of the scientific content.
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By bringing together experts across these multidisciplinary domains, we will identify drivers of innovation arising from the convergence of complementary fields of science and technology, as well as the chokepoints and needs of the communities contributing to this work. In addition, we will identify and discuss educational and workforce challenges and opportunities, and societal impacts including sustainability, ethics, and inclusion of marginalized groups.
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Goals: Consider what expertise and skills are needed to design, develop, analyze, and transition research advances Identify gaps and needs for education and workforce development Explore how to integrate biomaterials and biofabrication into learning curricula Explore how to introduce global awareness and sustainability into design thinking Livestream participants are encouraged to provide written reflections to the Google Jamboard 2:45–3:00 pm EST Key Takeaways from Day 1 Workshop Planning Committee END OF FIRST DAY 7
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9:30–10:15 am EST Breakout: Ethics, Risks, and Opportunities for Inclusion Facilitator: Deepti Tanjore, Advanced Biofuels Process Demonstration Unit (virtual) Goals: Identify key ethical considerations regarding biohybrid material design and implementation Explore the intersection between sustainability and material design, and identify areas of particular need or particular opportunity Explore how to incorporate diverse perspectives and communities in disruptive biohybrid material innovation Consider how scientific or national cultures may affect research conduct and progress with biohybrid materials Livestream participants are encouraged to provide written reflections to the Google Jamboard 10:15–10:30 am EST Break 10:30–11:30 am EST Panel: Plant-Based Technologies and Functional Materials Moderator: Megan Valentine, University of California, Santa Barbara (virtual)
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Goals: Building on the concepts identified in this workshop, identify key needs in biohybrid materials and technologies that are required to advance their adoption and implementation Identify areas of underinvestment, and gaps that are hindering progress Suggest means by which these needs can be addressed Livestream participants are encouraged to provide written reflections to the Google Jamboard 3:00 pm EST Closing Remarks Megan Valentine, University of California, Santa Barbara (virtual)
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Assign writing responsibilities and deadlines. 10:00–10:15 am EST Arrival and Sign-In 10:15–11:00 am EST Context Discussion The committee will discuss operational considerations and reports to help understand questions and context.
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By the end of the discussion, we hope to have a refined report outline and a short, preliminary list of scientific advances to include, vignettes to develop, and possible consensus findings, conclusions, and recommendations. 12:15–12:45 pm EST Lunch OPEN 1:00–2:00 pm EST Briefing 2:00–3:00 pm EST Briefing 3:00–3:45 pm EST Expert Discussion CLOSED 3:45–4:00 pm EST Consensus Findings, Conclusions, and Recommendations MEETING ADJOURNS Biotechnology Capabilities for National Security Needs Meeting 7 March 6, 2023 CLOSED Meeting Goals The goal of this meeting is to review the current report, finalize consensus findings, conclusions, and recommendations of the report, and gain committee approval for submitting the report to peer review.
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10:00–10:15 am EST Arrival and Sign-In 10:15 am–1:00 pm EST Report Review The committee will review the draft report. 1:00–1:30 pm EST Lunch 1:30–4:00 pm EST Discuss Reviewers' Comments, Edits, and Report Sign-Off The committee will discuss the reviewers' comments and revisions made in response to reviewers' comments.
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