Weighing the Options Criteria for Evaluating Weight-Management Programs (1995) / Chapter Skim
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10 Research and Policy Recommendations
10 Research and Policy Recommendations
Pages 163-170
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From page 163... ...
; and 2. increase in the number of obese people who are successful in attaining and maintaining relatively small weight losses (e.g., 10 percent of initial body weight)
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From page 164... ...
In addition, advances in molecular genetics have led to an understanding of the fundamental genetic defect in CF to the extent that gene-replacement therapy is being studied (Zabner et al., 1993~. One of the clinical benefits to date of this research into the molecular and genetic underpinnings of CF has been the development of aerosolized recombinant human DNAse, which is now used to make the secretions easier to expectorate (Davis, 1994; Fuchs et al., 1994~.
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From page 165... ...
spent approximately $35 million in fiscal year 1992 on direct research in obesity, representing about 10 percent of total NIH obligations in biomedical nutrition research and training that year, or 0.4 percent of total NIH research and training expenditures (NIH, 1994~. Given the magnitude of the problem of obesity in this country, we agree with a recent recommendation of the National Task Force on Prevention and Treatment of Obesity of NIH to double the current NIH expenditures on direct obesity research in real dollars over the next five years (NTF, 1994a)
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From page 166... ...
In addition, advances in molecular genetics have led to an understanding of the fundamental genetic defect in CF to the extent that gene-replacement therapy is being studied (Zabner et al., 1993~. One of the clinical benefits to date of this research into the molecular and genetic underpinnings of CF has been the development of aerosolized recombinant human DNAse, which is now used to make the secretions easier to expectorate (Davis, 1994; Fuchs et al., 1994~.
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From page 167... ...
Research approaches to identify and assess the multigenic components of obesity include the use of animal models and, in humans, studying twins and families. Further characterization of the human genome should aid in identification of the genetic components of human obesity, particularly as variable phenotypic expressions of obesity are better delineated.
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From page 168... ...
Public policies are needed to translate the research findings into usable information for the public and health-care providers and to create an environment that encourages the attainment and maintenance of healthy weight, healthful dietary patterns, and regular physical activity. As described throughout this report, obesity is a major public health problem and is arguably the main nutritional and metabolic disease in this country.
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From page 169... ...
Developing a research work force that can make the necessary discoveries and applications is going to require careful reevaluation of current training patterns and enhancement of training with a very strong interdisciplinary flavor. Research into the causes and, ultimately, the prevention of obesity requires people trained in the basic sciences as well as dietetics and the .
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From page 170... ...
Public policies are needed to translate the research findings into usable information for the public and health-care providers and to create an environment that encourages the attainment and maintenance of healthy weight, healthful dietary patterns, and regular physical activity. As described throughout this report, obesity is a major public health problem and is arguably the main nutritional and metabolic disease in this country.
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