Skip to main content

Currently Skimming:

Appendix G: Patient Summaries, Lilly Trial H3X-MC-PPPA
Pages 251-255

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 251...
... AST levels repeatedly ranged from 25-30 U/L and ALT likewise remained in the normal range. Lactate levels, performed at weekly intervals during the 2 months following cessation of therapy with FlAU, were always in the I.0-~.9 mmole/L range, (normal 0.3-2.6 mmole/~.
From page 252...
... Screening laboratory testing met study criteria. Liver biopsy had been performed earlier (February 15, 1993)
From page 253...
... TUFTS NEW ENGLAND MEDICAL CENTER SITE r ~ _~ The first patient treated with FTAU at Tufts New England Medical Center is a 38 year old man with a past history of alcohol and parenteral drug abuse; his chronic compensated HBV hepatitis was diagnosed in 1990. Liver biopsy one week before starting FlAU showed chronic active hepatitis (focal inflammatory infiltrate as well as piecemeal necrosis and bridging)
From page 254...
... Neurologic follow-ups on March 11, 1994 and on June 21, 1994 indicated that the patient continued to have numbness to the level of the knee and electric shock-like pains in the lower legs, preventing him from jogging or standing on his feet for any length of time, Subjectively the patient sensed that these symptoms had worsened over the 8 month period. Neurologic examinations showed loss of pain arid cold perception up to the knees, absent ankle jerks, absence of vibration sense in the great toes, arid some wasting of intrinsic foot muscles.
From page 255...
... The 5 patients received FTAU for 17-56 days. Serum HBV DNA levels decreased significantly in all patients during the first week of therapy and remained markedly lower throughout the treatment period.


This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
More information on Chapter Skim is available.