Prudent Practices in the Laboratory Handling and Disposal of Chemicals (1995) / Chapter Skim
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Prudent Planning of Experiments
Prudent Planning of Experiments
Pages 21-28
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From page 21... ...
" i, a. .::::, : ::':: :, ' ':.:':~:2: :':2S~2:':': IS,,,:: :~: .::: :.:.: :.~:: ::::: :: ;' .:i ::.' I''' - ;:i~ Prudent Planning of Experiments 2.A INTRODUCTION 2.B LEVELS OF FORMALITY IN EXPERIMENT PLANNING 22 22 2.C INDIVIDUAL RESPONSIBILITIES FOR PLANNING EXPERIMENTS 23 2.D INSTITUTIONAL POLICIES AND EMERGENCY RESPONSE PLANNING 2.E STEPS FOR PLANNING AN EXPERIMENT 2.E.1 Chapter 3: Evaluating Hazards and Assessing Risks in the Laboratory 2.E.2 Chapter 4: Management of Chemicals 2.E.3 Chapter 5: Working with Chemicals 2.E.4 Chapter 6: Working with Laboratory Equipment 2.E.5 Chapter 7: Disposal of Waste 2.E.6 Chapter 8: Laboratory Facilities 2.E.7 Chapter 9: Governmental Regulation of Laboratories 21 23 24 25 25 25 26 26 26 26
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From page 22... ...
In laboratories where this preliminary survey is routinely practiced, it has proved to be useful in both the maintenance of safe laboratory operations and the minimization of chemical exposure and waste generation. Because of the diversity of types of researchers and laboratory work, such processesboth formal and informal can help individuals associated with new, modified, or unfamiliar experiments or procedures to plan and work safely, responsibly, and productively.
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From page 23... ...
a formal hazard review process with complete written documentation of the procedures to be employed for new, unfamiliar, or intrinsically hazardous operations. For example, the following special areas of laboratory work will almost always require some approval steps: work with radioactive materials; experiments involving pathogens that cause serious or lethal infection; highand low-pressure work; research involving especially hazardous materials; and experiments being scaled up.
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From page 24... ...
A multipage inventory of complex names and structures of research chemicals, many of which never have been published in the literature, would be of little value to a public safety response team facing a laboratory fire. In planrung for emergencies, therefore, the actual needs of the responders should be the highest priority, and the appropriate level of information should be provided to ensure effective emergency response.
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From page 25... ...
2.E.2 Chapter 4: Management of Chemicals The experiment plan should include provisions for acquiring and storing chemicals and equipment to be used in the procedures. Some considerations for management of materials include effective labeling; inventory maintenance and reagent tracking; source reduction and materials sharing; compound shelf life; monitoring of reactive chemicals; hazards associated with storage of incompatibles, flammables, reactive chemicals, and so on; and the regulations governing shipping and storage of chemicals.
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From page 26... ...
Z.E.7 Chapter 9: Governmental Regulation of Laboratories Regulations are an intrinsic part of modern laboratory work that cannot be separated easily from other matters and should be considered at each step of experiment planning. It is only prudent for laboratory workers and supervisors to ensure regulatory compliance in conducting laboratory experiments.
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From page 27... ...
PRUDENT PLANNING OF EXPERIMENTS society, and the environment. While regulations are designed to protect these entities, not all regulations are sufficient or prudent in this regard.
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