Resource Sharing in Biomedical Research (1996) / Chapter Skim
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4: THE JACKSON LABORATORY
4: THE JACKSON LABORATORY
Pages 39-44
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From page 39... ...
) , other health organizations (Howard Hughes Medical Institute, American Cancer Society, American Health Association, Cystic Fibrosis Society, Multiple Sclerosis Society, March of Dimes, and others)
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From page 40... ...
These mice from external sources may be spontaneous mutations, or they may be induced mutations. The laboratory also maintains pedigreed stocks of mouse strains using breeding programs that are designed to ensure their genetically unique qualities.
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From page 41... ...
Any mouse stock acquired by TJL is rederived by cesarean section to eliminate the burden of infectious agents that might interfere with research, and the mutation is established on an inbred line. This importation policy reduces intercurrent disease, reduces mortality and morbidity, and enhances reproductive efficiency while decreasing the costs of monitoring for disease.
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From page 42... ...
Bioinformatics As part of its goal to educate scientists in research, TJL issues price lists, lists of stocks with genetic information, a quarterly newsletter, data sheets on individual strains, and special newsletters devoted to specific topics. The laboratory also publishes a handbook (updated every five years)
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From page 43... ...
This goes in large measure to the portions of the laboratory that are conducting basic genetic research, but even those units focused primarily on providing mice and related services to other scientists benefit from funding from NIH, NSF, the Howard Hughes Medical Institute, and a number of voluntary health organizations. The last of these are organizations such as the American Cancer Society, the Cystic Fibrosis Society, and the Multiple Sclerosis Society, which typically contribute amounts in the $10,000-$25,000 range for maintenance end production of mouse strains that are important to research on their own diseases.
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From page 44... ...
Like ATCC, The Jackson Laboratory puts institutional dollars into capital investments such as buildings, renovations, and equipment, as well as nonmonetary costs involved in providing resources for others. Muriel Davisson told the workshop that TJL is spending an incredible amount of institutional time negotiating agreements to obtain specific scientifically valuable mouse strains, despite the fact that these strains generate very little monetary return, either to TJL or to the people who contribute the mice.
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