Biographical Memoirs Volume 47 (1975) / Chapter Skim
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1 Paul Rufus Burkholder
1 Paul Rufus Burkholder
Pages 2-25
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When he was in graduate school, he compensated for some of his introvert tendencies by joining Gamma Alpha, a graduate student fraternity. There he found another "Burkie" (no relative)
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HIS INTELLECTUAL BASE The Burkholder forebears, religious refugees from the German section of Switzerland, came to Pennsylvania during its early colonial period. William Rankin Burkholder, Paul's father, was born in 1857, just before the Civil War, on a farm in central Pennsylvania.
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Rightly or wrongly, he felt that he was not so bright and must work extra hard to compensate. He took full advantage of the knowledge exhibited by the schoolmasters of the little village schools.
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His classes ranged over a great variety of subjects as available in a small liberal arts college. 1 ~ ~ ~ T He worked in the Bleary tor expense money.
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A job offer introduced him to the excitement of aquatic biology. The New York State Conservation Department offered him a summer job in the limnological survey of the state watersheds, beginning with the Cayuga Lake basin, with which he was already familiar.
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He taught the girls about germs, but now his interest in plant physiology returned. Avery started his work on plant hormones at Connecticut College and since it was a
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Dr. Sinnott went to Yale as chairman of the botany department and asked Burkholder to go with him as plant physiologist.
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His research moved apace, especially in microbiology, production of vitamins by yeasts, and production of antibiotics by lower fungi. CHLORAMPHENICOL DISCOVERED Burkholder soon made a dramatic discovery.
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Tatum left, Galston left, Naylor left, Burkholder left, and Bonner deserted the botany department for the medical school and a new department of micro
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He could be and was. The next five years at the Garden, with his old friend George Avery and with Sloan-Kettering cooperation, saw an intensive program of screening soil organisms for antibiotics that might have the potential for chemotherapy of cancer.
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He learned to scuba dive and examined corals, sponges, and seaweeds from the Caribbean to the Great Barrier Reef of Australia and the Philippines for possible sources of chemotherapeutic drugs. At the age of sixty-five, he retired from his Lamont Geological Observatory post and went to the University of Puerto Rico as a professor of marine biology at its laboratory in La Parguera and lastly to the College of the Virgin Islands.
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As a graduate student, he explored the gorges and forests around Ithaca. He explored Lake Erie for phytoplankton and later the waters of the Atlantic, the Caribbean, the South Pacific, and Antarctica.
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Fish. = Special Scientific Report, Fisheries 1930 Microplankton studies of Lake Erie.
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Polarized growth and cell studies on the Arena coleoptile, phyto-hormone test object.
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Studies on thiamine in green plants with the Phycomyces assay method.
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Vitamin content of some mature and germinated legume seeds. Plant Physiol., 20:301-6.
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III. Growth responses of virus tumors of Rumex to certain nucleic acid components and related compounds.
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Studies on B vitamins in relation to productivity of the Bahia Fosforescente, Puerto Rico.
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Measurements of productivity of turtle grass flats, reefs, and the Bahia Fosforescente of southern Puerto Rico. Publications of the Institute of Marine Science, University of Texas, Port Aransas, 6: 159-70.
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Estudio de los liquenes de Tierra del Fuego con especial consideration de suactividad antibiotica. Centro de Investigacion de Biologia Marina, Buenos Aires, Argentina.
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III. Chemical properties of some antibacterial compounds from marine sponges.
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Consequences of brine pollution in the Bahia Fosforescente, Puerto Rico. Limnol.
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Proximate analysis and amino acid composition of some marine phytoplankton and bacteria. Contribution no.
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