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Toxicologic Assessment of the Army's Zinc Cadmium Sulfide Dispersion Tests (1997) / Chapter Skim
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Toxicity and Related Data on Zinc Cadmium Sulfide
Pages 32-38

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From page 32...
... The sintered compound reportedly does not contain pure ZnS or CdS, because the sintering process is highly efficient (Sheila Fabiano, USR Optonix, Tnc., personal common., May 27, 1995~.
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From page 33...
... It can be made in the form of particles small enough to meet the criteria for studying atmospheric diffusion, and the dispersibility of ZnCdS is high enough to enable its practical use in the Army's dispersion tests Leighton 1955~. ZnCdS used in the Army's tests had a mass median aerodynamic diameter of 2-3 ~m, and the particle diameter ranged from 0.5 to 6.25 ,um.
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From page 34...
... 34 TOXICOLOGIC ASSESSMENT OF ZINC CADMIUM SULFIDE ZnS as cubic-~snc blend (sphalente)
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From page 35...
... The subcommittee believes that the lack of solubility of ZnCdS particles together with the limited toxicity studies implies that it will not be absorbed through the skin or gastrointestinal tract and that inhaled particles are not likely to be absorbed from the lung into blood for systemic distribution. Its lack of solubility also suggests that it is highly unlikely that Bee cadm~um ions would become bioavailable to target organs as a result of inhalation of ZnCdS, However, information is not available on whether ZnCdS might break down in the respiratory tract into more-soluble components, which could be easily absorbed into the body.
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From page 36...
... Because the phosphor mixture used in the LD50 study contained 65.4% liquid cosmetic base and about 35°/O ZnCdS, the highest dose of the mixture tested in dogs and rats contained ZnCdS at 3.5 and 7.0 g/kg of body weight, respectively. To avoid physical injury from the administration of massive doses, higher doses were not administered to the animals.
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From page 37...
... IMPLICATIONS OF VARIABLE COMPOSrTlON The Army asked that the National Research Council assess the toxicologic implications of the variable composition of ZnCdS used in the Army's tests. The subcommittee has reviewed the available information on the composition of ZnCdS used in the Army's tests and found no evidence of substantial variation in the amounts of zinc and cadmium in the sintered compound.
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From page 38...
... This information and the limited toxicity data available suggests that ZnCdS is not likely to show systemic toxicity. The subcommittee in its interim report (NRC ~ 995)
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Key Terms

  • toxicity studies
  • cadmium sulfide
  • cosmetic base
  • liquid cosmetic
  • respiratory tract

  • highly unlikely
  • gastrointestinal tract
  • toxicity data
  • tetrahedrally bonded
  • limited toxicity

  • zinc sulfide
  • sulfur atoms
  • sintering temperature
  • sulfide exists
  • atom tetrahedrally

  • studies conducted
  • dispersion tests
  • cubic form
  • dermal toxicity
  • systemic toxicity

  • oral studies
  • hexagonal form
  • particle diameter
  • arkansas department
  • white county

  • experimental animals
  • substantial variation
  • sulfur atom
  • mass median
  • structure containing


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