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Toxicologic Assessment of the Army's Zinc Cadmium Sulfide Dispersion Tests (1997) / Chapter Skim
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Glossary
Pages 360-366

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From page 361...
... Ames test - A relatively rapid and inexpensive screening procedure using bacteria to determine whether a substance causes mutations. ATSDR - Agency for Toxic Substances and Disease Registry.
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From page 362...
... cohort stu(ly - An epidemiologic study in which a defined group of persons known to be exposed to a potential disease risk factor is followed over time and compared to a group of persons who were not known to be exposed to the potential risk factor to evaluate the differences in rates of the outcome. Also termed a prospective study, follow-up study, incidence study, retrospective cohort, or historical cohort study.
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From page 363...
... An administered dose is the amount of substance administered to an animal or human, usually measured in milligrams per kilogram of body weight; milligrams per square meter of body surface area; or parts per million of the diet, drinking water, or ambient air. An effective dose is the amount of the substance reaching the target organ.
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From page 364...
... - The lowest dose of a chemical that produced an adverse effect when it was administered to animals in a toxicity study. malignant tumor - A tumor that has invaded neighboring tissue and/or undergone metastasis to distant body sites.
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From page 365...
... pollutant - Any material entering the environment whose nature, location, or quantity produces undesired effects. potency - The degree of ability to cause strong physiologic or toxic effects.
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From page 366...
... target organ - The specific organ affecter} by a close of a toxic substance; not necessarily the organ receiving the highest concentration. teratogen - Substance that causes birth defects (malformation or serious deviation from normal development of embryos and fetuses)
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Key Terms

  • toxic substance
  • contaminated media
  • genetic material
  • human exposure
  • environmental media

  • reference dose
  • risk factor
  • acceptable daily
  • exposure levels
  • cancer potency

  • toxicity study
  • risk agents
  • daily intake
  • agents acting
  • heritable changes

  • epidemiologic study
  • laboratory animals
  • receptor populations
  • health outcome
  • process wherein

  • toxic effects
  • adverse effect
  • initial contact
  • biologic effects
  • potency factor

  • mathematical description
  • combined biologic
  • body weight
  • brief exposure
  • produces risk


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